Sensor-less checkpoint activation?

Rhett Michelson, Ted Weinert

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

DNA damage activates a set of proteins whose job is to delay the cell cycle until the damage is repaired. This process was thought to involve the detection of damage by sensor proteins, which transmit a signal to a key protein kinase and thence to downstream targets. Unexpectedly, damage can also activate the kinase directly.

Original languageEnglish (US)
Pages (from-to)E177-E179
JournalNature Cell Biology
Volume1
Issue number7
DOIs
StatePublished - Nov 1999

ASJC Scopus subject areas

  • Cell Biology

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