Short wavelength light administered just prior to waking: A pilot study

Michael A. Grandner, Daniel F. Kripke, Jeffrey Elliott, Roger Cole

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Bright light in the blue-green range, administered in the early morning hours (prior to waking) may be particularly effective in shifting circadian rhythms and may increase gonadotropin production. Accordingly, we tested the feasibility and utility of a mask that emits bright blue/green light (compared to a similar mask that emitted a dim red light) towards the end of sleep in a randomized, placebocontrolled pilot study. The study included a three-day baseline period, immediately followed by a 12-day intervention period. Subjects were 30 healthy young men with minimal-mild depression. The bright light masks were welltolerated and demonstrated adequate safety and feasibility. Following the intervention, those who wore the bright light mask demonstrated altered sleep timing suggestive of an earlier sleep period, and excreted a slight increase in follicle-stimulating hormone (FSH). Overall, light masks may prove useful in future studies of bright light therapy.

Original languageEnglish (US)
Pages (from-to)13-32
Number of pages20
JournalBiological Rhythm Research
Volume44
Issue number1
DOIs
StatePublished - Feb 18 2013
Externally publishedYes

Fingerprint

Masks
wavelengths
sleep
wavelength
Light
Sleep
follicle-stimulating hormone
Methyl Green
gonadotropins
red light
Phototherapy
circadian rhythm
Follicle Stimulating Hormone
Circadian Rhythm
Gonadotropins
Depression
Safety
hormone
safety

Keywords

  • Circadian rhythms
  • Depression
  • Hormones
  • Light
  • Sleep

ASJC Scopus subject areas

  • Physiology
  • Ecology, Evolution, Behavior and Systematics
  • Physiology (medical)

Cite this

Short wavelength light administered just prior to waking : A pilot study. / Grandner, Michael A.; Kripke, Daniel F.; Elliott, Jeffrey; Cole, Roger.

In: Biological Rhythm Research, Vol. 44, No. 1, 18.02.2013, p. 13-32.

Research output: Contribution to journalArticle

Grandner, Michael A. ; Kripke, Daniel F. ; Elliott, Jeffrey ; Cole, Roger. / Short wavelength light administered just prior to waking : A pilot study. In: Biological Rhythm Research. 2013 ; Vol. 44, No. 1. pp. 13-32.
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