Shrimp antimicrobial testing. I. in vitro susceptibility of thirteen gram-negative bacteria to twelve antimicrobials

Leone L. Mohney, Thomas A. Bell, Donald V Lightner

Research output: Contribution to journalArticle

30 Scopus citations


Standard minimum inhibitory concentration (MIC studies were conducted in vitro on eleven prospective antimicrobials and one reference antimicrobial. The compounds were tested against a standardized battery of l3 gram-negative bacterial isolates associated with shrimp disease. Two additional bacterial organisms not associated with shrimp, Escherichia coli and Pseudomonas aeruginosa, were also tested as system controls. The compounds tested were chloramphenicol (reference), enrofloxacin, erythromycin, florfenicol, oxytetracycline, paromomycin, four experimental fluoroquinolines (PD124816, PD127391, PD131628, PD132133), Romet-30®, and Sara-fin®. All compounds, with the possible exception of paromomycin, had significantly better overall MIC ranges than did chloramphenicol.

Original languageEnglish (US)
Pages (from-to)257-261
Number of pages5
JournalJournal of Aquatic Animal Health
Issue number4
StatePublished - 1992


ASJC Scopus subject areas

  • Aquatic Science

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