Siberian genetic diversity reveals complex origins of the Samoyedic-speaking populations

Tatiana Karafet, Ludmila P. Osipova, Olga V. Savina, Brian Hallmark, Michael F Hammer

Research output: Contribution to journalArticle

Abstract

Objectives: We examined autosomal genome-wide SNPs and Y-chromosome data from 15 Siberian and 12 reference populations to study the affinities of Siberian populations, and to address hypotheses about the origin of the Samoyed peoples. Methods: Samples were genotyped for 567 096 autosomal SNPs and 147 Y-chromosome polymorphic sites. For several analyses, we used 281 093 SNPs from the intersection of our data with publicly available ancient Siberian samples. To examine genetic relatedness among populations, we applied PCA, FST, TreeMix, and ADMIXTURE analyses. To explore the potential effect of demography and evolutionary processes, the distribution of ROH and IBD sharing within population were studied. Results: Analyses of autosomal and Y-chromosome data reveal high differentiation of the Siberian groups. The Siberian populations have a large proportion of their genome in ROH and IBD segments. Several populations (ie, Nganasans, Evenks, Yukagirs, and Koryaks) do not appear to have experienced admixture with other Siberian populations (ie, producing only positive f3), while for the other tested populations the composition of mixing sources always included Nganasans or Evenks. The Nganasans from the Taymyr Peninsula demonstrate the greatest level of shared shorter ROH and IBD with nearly all other Siberian populations. Conclusions: Autosomal SNP and Y-chromosome data demonstrate that Samoyedic populations differ significantly in their genetic composition. Genetic relationship is observed only between Forest and Tundra Nentsi. Selkups are affiliated with the Kets from the Yenisey River, while the Nganasans are separated from their linguistic neighbors, showing closer affinities with the Evenks and Yukagirs.

Original languageEnglish (US)
Article numbere23194
JournalAmerican Journal of Human Biology
DOIs
StateAccepted/In press - Jan 1 2018

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speaking
chromosome
genetic variation
Population
Y Chromosome
Y chromosome
genome
Single Nucleotide Polymorphism
demography
tundra
relatedness
genetic relationships
genetic diversity
Genome
Chromosomes, Human, Pair 15
Passive Cutaneous Anaphylaxis
river
Linguistics
Rivers
Demography

ASJC Scopus subject areas

  • Anatomy
  • Ecology, Evolution, Behavior and Systematics
  • Anthropology
  • Genetics

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Siberian genetic diversity reveals complex origins of the Samoyedic-speaking populations. / Karafet, Tatiana; Osipova, Ludmila P.; Savina, Olga V.; Hallmark, Brian; Hammer, Michael F.

In: American Journal of Human Biology, 01.01.2018.

Research output: Contribution to journalArticle

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AU - Hammer, Michael F

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