Single concentration tests show synergism among Bacillus thuringiensis subsp. israelensis toxins against the malaria vector mosquito Anopheles albimanus

María Teresa Fernández-Luna, Bruce E Tabashnik, Humberto Lanz-Mendoza, Alejandra Bravo, Mario Soberón, Juan Miranda-Ríos

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Bioassays of insecticidal proteins from Bacillus thuringiensis subsp. israelensis with larvae of the malaria vector mosquito Anopheles albimanus showed that the cytolytic protein Cyt1Aa was not toxic alone, but it increased the toxicity of the crystalline proteins Cry4Ba and Cry11Aa. Synergism also occurred between Cry4Ba and Cry11Aa toxins. Whereas many previous analyses of synergism have been based on a series of toxin concentrations leading to comparisons between expected and observed values for the concentration killing 50% of insects tested (LC50), we describe and apply a method here that enables testing for synergism based on single concentrations of toxins.

Original languageEnglish (US)
Pages (from-to)231-233
Number of pages3
JournalJournal of Invertebrate Pathology
Volume104
Issue number3
DOIs
StatePublished - Jul 2010

Fingerprint

Anopheles albimanus
Bacillus thuringiensis subsp. israelensis
Bacillus thuringiensis
Anopheles
synergism
malaria
mosquito
toxin
Malaria
Culicidae
toxins
protein
insecticidal proteins
Proteins
Poisons
testing
lethal concentration 50
Biological Assay
Larva
Insects

Keywords

  • Anopheles albimanus
  • Bacillus thuringiensis subsp. israelensis
  • Cry11Aa
  • Cry4Ba
  • Cyt1Aa
  • Malaria
  • Synergism

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Medicine(all)

Cite this

Single concentration tests show synergism among Bacillus thuringiensis subsp. israelensis toxins against the malaria vector mosquito Anopheles albimanus. / Fernández-Luna, María Teresa; Tabashnik, Bruce E; Lanz-Mendoza, Humberto; Bravo, Alejandra; Soberón, Mario; Miranda-Ríos, Juan.

In: Journal of Invertebrate Pathology, Vol. 104, No. 3, 07.2010, p. 231-233.

Research output: Contribution to journalArticle

Fernández-Luna, María Teresa ; Tabashnik, Bruce E ; Lanz-Mendoza, Humberto ; Bravo, Alejandra ; Soberón, Mario ; Miranda-Ríos, Juan. / Single concentration tests show synergism among Bacillus thuringiensis subsp. israelensis toxins against the malaria vector mosquito Anopheles albimanus. In: Journal of Invertebrate Pathology. 2010 ; Vol. 104, No. 3. pp. 231-233.
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