Small form factor, flexible, dual-modality handheld probe for smartphone-based, point-of-care oral and oropharyngeal cancer screening

Ross D. Uthoff, Bofan Song, Sumsum Sunny, Sanjana Patrick, Amritha Suresh, Trupti Kolur, Keerthi Gurushanth, Kimberly Wooten, Vishal Gupta, Mary E. Platek, Anurag K. Singh, Petra Wilder-Smith, Moni Abraham Kuriakose, Praveen Birur, Rongguang Liang

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Oral cancer is a growing health issue in low- and middle-income countries due to betel quid, tobacco, and alcohol use and in younger populations of middle- and high-income communities due to the prevalence of human papillomavirus. The described point-of-care, smartphone-based intraoral probe enables autofluorescence imaging and polarized white light imaging in a compact geometry through the use of a USB-connected camera module. The small size and flexible imaging head improves on previous intraoral probe designs and allows imaging the cheek pockets, tonsils, and base of tongue, the areas of greatest risk for both causes of oral cancer. Cloud-based remote specialist and convolutional neural network clinical diagnosis allow for both remote community and home use. The device is characterized and preliminary field-testing data are shared.

Original languageEnglish (US)
Article number106003
JournalJournal of biomedical optics
Volume24
Issue number10
DOIs
StatePublished - Oct 1 2019

Keywords

  • autofluorescence imaging
  • biomedical imaging
  • mobile health
  • oral cancer screening

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Biomedical Engineering

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