Smartphone-Based lab-on-a-chip sensor for flu detection

Research output: Contribution to journalArticle

Abstract

It is desirable to conduct reverse transcription polymerase chain reaction (RT-PCR) or an immunoassay at the point-of-care level or in the field for early diagnosis of influenza. The lab-on-a-chip (LOC) is the perfect instrument to perform such a task. An LOC is a network of channels and wells that is etched onto a silicon or polymer substrate to build a miniature laboratory. The LOC enables sample handing, mixing, dilution, separation, staining, and detection within a single, integrated system and is perfectly suitable for chemical or biological assays. Final detections in an LOC can be made electrochemically or optically, but optical detection is gaining popularity due to its high sensitivity and better specificity. Optical detection in an LOC can be implemented through the use of an LED light source, a pair of optical fibers, and a miniature spectrometer.

Original languageEnglish (US)
Pages (from-to)20-22
Number of pages3
JournalResource: Engineering and Technology for Sustainable World
Volume21
Issue number1
StatePublished - Jan 2014

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Point-of-Care Systems
Optical Fibers
Lab-on-a-chip
Smartphones
Silicon
Immunoassay
influenza
Biological Assay
Human Influenza
Reverse Transcription
sensors (equipment)
Early Diagnosis
Polymers
Staining and Labeling
Light
Sensitivity and Specificity
Polymerase Chain Reaction
Sensors
early diagnosis
silicon

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biotechnology
  • Engineering(all)

Cite this

Smartphone-Based lab-on-a-chip sensor for flu detection. / Yoon, Jeong-Yeol.

In: Resource: Engineering and Technology for Sustainable World, Vol. 21, No. 1, 01.2014, p. 20-22.

Research output: Contribution to journalArticle

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