Abstract
Phosphorane ylides and phosphonate anions react smoothly with resin-bound aldehydes and ketones to provide alkenes in good yields and purities (assessed after cleavage of acid-labile PAL anchor to support). The reactions of aldehydes give excellent stereoselectivities. Effective conditions have been developed for carrying out these transformations.
Original language | English (US) |
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Pages (from-to) | 1697-1702 |
Number of pages | 6 |
Journal | Collection of Czechoslovak Chemical Communications |
Volume | 61 |
Issue number | 12 |
DOIs | |
State | Published - Dec 1996 |
Externally published | Yes |
Keywords
- Combinatorial chemistry
- Solid-phase synthesis
- Wittig reaction
ASJC Scopus subject areas
- Chemistry(all)