The purpose of this work was to derive an equation for the rapid estimation of octanol solubilities of organic compounds. Solubilities ranging over 4 orders of magnitude were predicted with an average absolute error of 0.39 logarithmic units using melting point alone. The greatest error in prediction occurred for strongly bonded compounds.
|Original language||English (US)|
|Publication status||Published - 2006|
ASJC Scopus subject areas
- Molecular Medicine
- Pharmaceutical Science