Solubilization of some low-polarity organic compounds by hydroxypropyl- β-cyclodextrin

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Abstract

Hydroxypropyl-β-cyclodextrin (HPCD), a microbially produced compound, was investigated for its potential to increase the apparent aqueous solubilities of low-polarity organic compounds. The results show that the apparent solubilities of trichloroethene, chlorobenzene, naphthalene, anthracene, and p,p'-DDT were significantly increased in HPCD solutions. The relative aqueous-phase concentrations (S(t)/S(o)) of the compounds increased linearly with increasing HPCD concentration. The solubilization power of HPCD is dependent on the size and relative polarity of its cavity, and, unlike micelle-forming surfactants, HPCD has no critical micelle concentration. The partition mechanism was shown to be a valid approach for interpreting the solubilization activity of HPCD. The potential application of HPCD in the remediation of contaminated groundwater is briefly discussed.

Original languageEnglish (US)
Pages (from-to)2821-2825
Number of pages5
JournalEnvironmental Science and Technology
Volume27
Issue number13
DOIs
Publication statusPublished - 1993

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ASJC Scopus subject areas

  • Environmental Engineering
  • Environmental Science(all)
  • Environmental Chemistry

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