Solubilization of the neutral and charged forms of 2,4,6-trichlorophenol by hydroxypropyl-β-cyclodextrin, or methyl-β-cyclodextrin in water

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5 Citations (Scopus)

Abstract

The solubility of 2,4,6-trichlorophenol (TCP) in hydroxypropyl-β- cyclodextrin (HPβCD), or methyl-β-cyclodextrin (MeβCD) at pH 3.0 and 8.8 reported by Hanna et al. [J. Hazard. Mater. B100 (2003) 109] is reevaluated in this paper. The complexations of the individual dissolved forms were examined. As expected, the neutral TCP complexes more strongly with the cyclodextrins than the charged species. However, in spite of its lower complexation constant, the charged form of TCP forms more complex with each CD, and thus is solubilized to a greater extent.

Original languageEnglish (US)
Pages (from-to)129-131
Number of pages3
JournalJournal of Hazardous Materials
Volume108
Issue number1-2
DOIs
StatePublished - Apr 30 2004

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Cyclodextrins
solubilization
complexation
Complexation
Water
solubility
hazard
water
Solubility
Hazards
Mothers
2,4,6-trichlorophenol

Keywords

  • 2,4,6-Trichlorophenol (TCP)
  • Complexation
  • Hydroxypropyl-β-cyclodextrin (HPβCD)
  • Methyl-β-cyclodextrin (MeβCD)
  • Solubilization

ASJC Scopus subject areas

  • Chemical Health and Safety
  • Process Chemistry and Technology
  • Safety, Risk, Reliability and Quality
  • Environmental Engineering

Cite this

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title = "Solubilization of the neutral and charged forms of 2,4,6-trichlorophenol by hydroxypropyl-β-cyclodextrin, or methyl-β-cyclodextrin in water",
abstract = "The solubility of 2,4,6-trichlorophenol (TCP) in hydroxypropyl-β- cyclodextrin (HPβCD), or methyl-β-cyclodextrin (MeβCD) at pH 3.0 and 8.8 reported by Hanna et al. [J. Hazard. Mater. B100 (2003) 109] is reevaluated in this paper. The complexations of the individual dissolved forms were examined. As expected, the neutral TCP complexes more strongly with the cyclodextrins than the charged species. However, in spite of its lower complexation constant, the charged form of TCP forms more complex with each CD, and thus is solubilized to a greater extent.",
keywords = "2,4,6-Trichlorophenol (TCP), Complexation, Hydroxypropyl-β-cyclodextrin (HPβCD), Methyl-β-cyclodextrin (MeβCD), Solubilization",
author = "Yan He and Yalkowsky, {Samuel H}",
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journal = "Journal of Hazardous Materials",
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TY - JOUR

T1 - Solubilization of the neutral and charged forms of 2,4,6-trichlorophenol by hydroxypropyl-β-cyclodextrin, or methyl-β-cyclodextrin in water

AU - He, Yan

AU - Yalkowsky, Samuel H

PY - 2004/4/30

Y1 - 2004/4/30

N2 - The solubility of 2,4,6-trichlorophenol (TCP) in hydroxypropyl-β- cyclodextrin (HPβCD), or methyl-β-cyclodextrin (MeβCD) at pH 3.0 and 8.8 reported by Hanna et al. [J. Hazard. Mater. B100 (2003) 109] is reevaluated in this paper. The complexations of the individual dissolved forms were examined. As expected, the neutral TCP complexes more strongly with the cyclodextrins than the charged species. However, in spite of its lower complexation constant, the charged form of TCP forms more complex with each CD, and thus is solubilized to a greater extent.

AB - The solubility of 2,4,6-trichlorophenol (TCP) in hydroxypropyl-β- cyclodextrin (HPβCD), or methyl-β-cyclodextrin (MeβCD) at pH 3.0 and 8.8 reported by Hanna et al. [J. Hazard. Mater. B100 (2003) 109] is reevaluated in this paper. The complexations of the individual dissolved forms were examined. As expected, the neutral TCP complexes more strongly with the cyclodextrins than the charged species. However, in spite of its lower complexation constant, the charged form of TCP forms more complex with each CD, and thus is solubilized to a greater extent.

KW - 2,4,6-Trichlorophenol (TCP)

KW - Complexation

KW - Hydroxypropyl-β-cyclodextrin (HPβCD)

KW - Methyl-β-cyclodextrin (MeβCD)

KW - Solubilization

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JF - Journal of Hazardous Materials

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