Sonoelastography of the common flexor tendon of the elbow with histologic agreement: A cadaveric study

Andrea S. Klauser, Mathias J. Pamminger, Ethan J. Halpern, Mohamed M.H. Abd Ellah, Bernhard Moriggl, Mihra Taljanovic, Christian Deml, Judith Sztankay, Guenter Klima, Leonhard Gruber, Werner R. Jaschke

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9 Scopus citations

Abstract

Purpose: To determine the correlation of the results of conventional B-mode ultrasonography (US) and compression sonoelastography with histologic results in common flexor tendons of the elbow in human cadavers. Materials and Methods: Twenty-five common flexor tendons were evaluated in 16 fresh, unembalmed cadavers of 11 women with a median age of 85 years (range, 71-101 years) and five men with a median age of 78 years (range, 70-88 years). Informed consent was provided according to the last will of the donors. B-mode US results were classified as grade 1, normal tendon with homogeneous fibrillar pattern; grade 2, tendon thickening or hypoechoic areas and/or calcifications in less than 30% of the tendon; or grade 3, hypoechoic areas and/or calcifications greater than 30% of the tendon. Sonoelastographic results were grade 1, blue (hardest) to green (hard); grade 2, yellow (soft); and grade 3, red (softest). The intraclass correlation coefficient was calculated to determine agreement with histologic findings for each B-mode US, sonoelastographic, and combined B-mode US and sonoelastographic examination. Histologic results were grade 1, normal, with parallel fibrillar pattern; grade 2, mild tendinopathy, with cellular infiltration, angiogenesis, or fatty vacuoles; or grade 3, severe tendinopathy, with loss of parallel collagen structure and necrosis. Results: Histologic alterations were detected in 44% (11 of 25) of biopsy specimens. Intraclass correlation with histologic results was 0.57 for B-mode US, 0.68 for sonoelastography, and 0.84 for the combination of the two approaches. Conclusion: The addition of sonoelastography to B-mode US provided statistically significant improvement in correlation with histologic results compared with the use of B-mode US alone (P <.02).

Original languageEnglish (US)
Pages (from-to)486-491
Number of pages6
JournalRadiology
Volume283
Issue number2
DOIs
StatePublished - May 1 2017

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    Klauser, A. S., Pamminger, M. J., Halpern, E. J., Abd Ellah, M. M. H., Moriggl, B., Taljanovic, M., Deml, C., Sztankay, J., Klima, G., Gruber, L., & Jaschke, W. R. (2017). Sonoelastography of the common flexor tendon of the elbow with histologic agreement: A cadaveric study. Radiology, 283(2), 486-491. https://doi.org/10.1148/radiol.2016160139