Southern regional trophoblastic disease center, 1972-1977

Kenneth D Hatch, Hugh M. Shlngleton, J. Max Austin, Larry R. Boots, J. Benjamin Younger, Seng Jaw Soong

Research output: Contribution to journalArticle

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Abstract

The experience of the Southern Regional Trophoblastic Disease Center includes 222 patients who were referred from January 1972 to October 1977. The initial tissue diagnosis was hydatidiform mole in 212 patients and choriocarcinoma in ten. There was spontaneous remission of 142 (69%) of the moles and one of the choriocarcinomas, and 77 patients developed persistent trophoblastic disease. Of these, 58 had no evidence of metastasis, and all achieved remission with single-drug therapy. Nineteen patients developed metastases; 13 were in the "good prognosis" category, and all achieved remission with single-drug therapy. Five (83%) of the six patients with metastases in the "poor prognosis" group achieved remission with triple chemotherapy; one died of her disease.

Original languageEnglish (US)
JournalSouthern Medical Journal
Volume71
Issue number11
StatePublished - 1978
Externally publishedYes

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Choriocarcinoma
Neoplasm Metastasis
Drug Therapy
Spontaneous Remission
Hydatidiform Mole

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Hatch, K. D., Shlngleton, H. M., Max Austin, J., Boots, L. R., Benjamin Younger, J., & Soong, S. J. (1978). Southern regional trophoblastic disease center, 1972-1977. Southern Medical Journal, 71(11).

Southern regional trophoblastic disease center, 1972-1977. / Hatch, Kenneth D; Shlngleton, Hugh M.; Max Austin, J.; Boots, Larry R.; Benjamin Younger, J.; Soong, Seng Jaw.

In: Southern Medical Journal, Vol. 71, No. 11, 1978.

Research output: Contribution to journalArticle

Hatch, KD, Shlngleton, HM, Max Austin, J, Boots, LR, Benjamin Younger, J & Soong, SJ 1978, 'Southern regional trophoblastic disease center, 1972-1977', Southern Medical Journal, vol. 71, no. 11.
Hatch KD, Shlngleton HM, Max Austin J, Boots LR, Benjamin Younger J, Soong SJ. Southern regional trophoblastic disease center, 1972-1977. Southern Medical Journal. 1978;71(11).
Hatch, Kenneth D ; Shlngleton, Hugh M. ; Max Austin, J. ; Boots, Larry R. ; Benjamin Younger, J. ; Soong, Seng Jaw. / Southern regional trophoblastic disease center, 1972-1977. In: Southern Medical Journal. 1978 ; Vol. 71, No. 11.
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