Spatial cognition and the hippocampus: The anterior-posterior axis

Lynn Nadel, Siobhan Hoscheidt, T Lee Ryan

Research output: Contribution to journalArticle

69 Citations (Scopus)

Abstract

We discuss the question of differentiation along the anterior- posterior longitudinal axis of the hippocampus. Data from a recent fMRI study are reanalyzed to determine whether activations in these hippocampal regions are affected by the nature of the information being accessed during a scanning session in which participants thought about episodes from their lives. Retrieving detailed spatial relational information preferentially activated the posterior hippocampus, whereas retrieving information about locales (or contexts) preferentially activated the anterior hippocampus. These data support the view that there is functional differentiation along the longitudinal axis in humans that matches what has been seen in rats, namely, that the posterior (dorsal) hippocampus is crucial for precise spatial behavior, and the anterior (ventral) hippocampus is crucial for context coding.

Original languageEnglish (US)
Pages (from-to)22-28
Number of pages7
JournalJournal of Cognitive Neuroscience
Volume25
Issue number1
DOIs
StatePublished - Jan 2013

Fingerprint

Cognition
cognition
Hippocampus
functional differentiation
activation
Spatial Behavior
coding
Magnetic Resonance Imaging
Spatial Cognition

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Language and Linguistics
  • Linguistics and Language

Cite this

Spatial cognition and the hippocampus : The anterior-posterior axis. / Nadel, Lynn; Hoscheidt, Siobhan; Ryan, T Lee.

In: Journal of Cognitive Neuroscience, Vol. 25, No. 1, 01.2013, p. 22-28.

Research output: Contribution to journalArticle

@article{75f4d978abc74175abc339e3ad48da72,
title = "Spatial cognition and the hippocampus: The anterior-posterior axis",
abstract = "We discuss the question of differentiation along the anterior- posterior longitudinal axis of the hippocampus. Data from a recent fMRI study are reanalyzed to determine whether activations in these hippocampal regions are affected by the nature of the information being accessed during a scanning session in which participants thought about episodes from their lives. Retrieving detailed spatial relational information preferentially activated the posterior hippocampus, whereas retrieving information about locales (or contexts) preferentially activated the anterior hippocampus. These data support the view that there is functional differentiation along the longitudinal axis in humans that matches what has been seen in rats, namely, that the posterior (dorsal) hippocampus is crucial for precise spatial behavior, and the anterior (ventral) hippocampus is crucial for context coding.",
author = "Lynn Nadel and Siobhan Hoscheidt and Ryan, {T Lee}",
year = "2013",
month = "1",
doi = "10.1162/jocn_a_00313",
language = "English (US)",
volume = "25",
pages = "22--28",
journal = "Journal of Cognitive Neuroscience",
issn = "0898-929X",
publisher = "MIT Press Journals",
number = "1",

}

TY - JOUR

T1 - Spatial cognition and the hippocampus

T2 - The anterior-posterior axis

AU - Nadel, Lynn

AU - Hoscheidt, Siobhan

AU - Ryan, T Lee

PY - 2013/1

Y1 - 2013/1

N2 - We discuss the question of differentiation along the anterior- posterior longitudinal axis of the hippocampus. Data from a recent fMRI study are reanalyzed to determine whether activations in these hippocampal regions are affected by the nature of the information being accessed during a scanning session in which participants thought about episodes from their lives. Retrieving detailed spatial relational information preferentially activated the posterior hippocampus, whereas retrieving information about locales (or contexts) preferentially activated the anterior hippocampus. These data support the view that there is functional differentiation along the longitudinal axis in humans that matches what has been seen in rats, namely, that the posterior (dorsal) hippocampus is crucial for precise spatial behavior, and the anterior (ventral) hippocampus is crucial for context coding.

AB - We discuss the question of differentiation along the anterior- posterior longitudinal axis of the hippocampus. Data from a recent fMRI study are reanalyzed to determine whether activations in these hippocampal regions are affected by the nature of the information being accessed during a scanning session in which participants thought about episodes from their lives. Retrieving detailed spatial relational information preferentially activated the posterior hippocampus, whereas retrieving information about locales (or contexts) preferentially activated the anterior hippocampus. These data support the view that there is functional differentiation along the longitudinal axis in humans that matches what has been seen in rats, namely, that the posterior (dorsal) hippocampus is crucial for precise spatial behavior, and the anterior (ventral) hippocampus is crucial for context coding.

UR - http://www.scopus.com/inward/record.url?scp=84870378446&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84870378446&partnerID=8YFLogxK

U2 - 10.1162/jocn_a_00313

DO - 10.1162/jocn_a_00313

M3 - Article

C2 - 23198887

AN - SCOPUS:84870378446

VL - 25

SP - 22

EP - 28

JO - Journal of Cognitive Neuroscience

JF - Journal of Cognitive Neuroscience

SN - 0898-929X

IS - 1

ER -