Spontaneous fatal sarcocystosis in a calf

John A Schmitz, W. W. Wolf

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Recent experiments have established that the coccidian parasite Sarcocystis can be pathogenic for cattle. A case of Sarcocystis infection was found in a 2 wk old calf which died after an illness of 2-3 days. At autopsy, the pleural cavity had 1 l of yellow fluid with fibrin. The lungs were edematous and the ventral portions consolidated. The peritoneal cavity contained 200-300 ml of clear fluid; the liver was extremely large. After embedding in paraffin, sections (6 μ) were stained with HE, PAS and the Wolbach-Giemsa stain. Specimens of lung also were prepared for electron microscopy. Microscopy showed dense foci of lymphocytes primarily in the renal cortex. Scattered through the cortex were many schizonts that were lightly basophilic with coarse hyperbasophilic granules. They were from 4 to 19.2 μ wide and 9.6 to 24 μ long. The schizonts were scattered singly and in clusters in glomeruli and interstitial tissues. Some bulged into tubular lumina. Some glomeruli were in degenerative stages and contained necrotic cells whilst others had hyalinized tufts. Schizonts infected the endothelial cells of a few small arteries. The liver showed congestion and necrosis of hepatocytes. Some schizonts, identical to those in the kidney, were present in the Kuppfer cells, hepatocytes and portal areas. The lungs had diffuse interstitial pneumonia with edematous interlobar septa and had diffuse and focal lymphocytic infiltrates, many immature and a few mature schizonts. The pleura and heart muscle contained scattered schizonts. Elecron microscopy showed that the schizonts were intracytoplasmic and had a double-membrane outer wall or pellicle. Immature and mature schizonts were quite different. The schizonts found in this calf closely resembled those in tissues of calves experimentally infected with S. fusiformis. It was apparent that the cause of death was an overwhelming Sarcocystis infection.

Original languageEnglish (US)
Pages (from-to)527-531
Number of pages5
JournalVeterinary Pathology
Volume14
Issue number5
StatePublished - 1977
Externally publishedYes

Fingerprint

Sarcocystosis
sarcocystosis
Schizonts
schizonts
calves
Sarcocystis
lungs
Lung
hepatocytes
Microscopy
Hepatocytes
microscopy
cortex
immatures
Paraffin Embedding
kidneys
Azure Stains
pleura
Kidney
Pleural Cavity

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Spontaneous fatal sarcocystosis in a calf. / Schmitz, John A; Wolf, W. W.

In: Veterinary Pathology, Vol. 14, No. 5, 1977, p. 527-531.

Research output: Contribution to journalArticle

Schmitz, JA & Wolf, WW 1977, 'Spontaneous fatal sarcocystosis in a calf', Veterinary Pathology, vol. 14, no. 5, pp. 527-531.
Schmitz, John A ; Wolf, W. W. / Spontaneous fatal sarcocystosis in a calf. In: Veterinary Pathology. 1977 ; Vol. 14, No. 5. pp. 527-531.
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