Spontaneous Physical Activity Defends Against Obesity

Catherine M. Kotz, Claudio E. Perez-Leighton, Jennifer A Teske, Charles J. Billington

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

PURPOSE OF REVIEW: Spontaneous physical activity (SPA) is a physical activity not motivated by a rewarding goal, such as that associated with food-seeking or wheel-running behavior. SPA is often thought of as only "fidgeting," but that is a mischaracterization, since fidgety behavior can be linked to stereotypies in neurodegenerative disease and other movement disorders. Instead, SPA should be thought of as all physical activity behavior that emanates from an unconscious drive for movement.

RECENT FINDINGS: An example of this may be restless behavior, which can include fidgeting and gesticulating, frequent sit-to-stand movement, and more time spent standing and moving. All physical activity burns calories, and as such, SPA could be manipulated as a means to burn calories, and defend against weight gain and reduce excess adiposity. In this review, we discuss human and animal literature on the use of SPA in reducing weight gain, the neuromodulators that could be targeted to this end, and future directions in this field.

Original languageEnglish (US)
Pages (from-to)362-370
Number of pages9
JournalCurrent obesity reports
Volume6
Issue number4
DOIs
StatePublished - Dec 1 2017

Fingerprint

Obesity
Weight Gain
Adiposity
Movement Disorders
Burns
Running
Neurodegenerative Diseases
Neurotransmitter Agents
Food

Keywords

  • Animal
  • Brain
  • Central nervous system
  • DREADD
  • Dynorphin
  • Eating behavior
  • Exercise
  • Food intake
  • Human
  • Locomotion
  • Non-exercise energy expenditure
  • Obesity
  • Optogenetics
  • Orexin
  • Spontaneous physical activity

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Spontaneous Physical Activity Defends Against Obesity. / Kotz, Catherine M.; Perez-Leighton, Claudio E.; Teske, Jennifer A; Billington, Charles J.

In: Current obesity reports, Vol. 6, No. 4, 01.12.2017, p. 362-370.

Research output: Contribution to journalReview article

Kotz, CM, Perez-Leighton, CE, Teske, JA & Billington, CJ 2017, 'Spontaneous Physical Activity Defends Against Obesity', Current obesity reports, vol. 6, no. 4, pp. 362-370. https://doi.org/10.1007/s13679-017-0288-1
Kotz, Catherine M. ; Perez-Leighton, Claudio E. ; Teske, Jennifer A ; Billington, Charles J. / Spontaneous Physical Activity Defends Against Obesity. In: Current obesity reports. 2017 ; Vol. 6, No. 4. pp. 362-370.
@article{6d1c27f7214b4fa580be4649ffc4b0bb,
title = "Spontaneous Physical Activity Defends Against Obesity",
abstract = "PURPOSE OF REVIEW: Spontaneous physical activity (SPA) is a physical activity not motivated by a rewarding goal, such as that associated with food-seeking or wheel-running behavior. SPA is often thought of as only {"}fidgeting,{"} but that is a mischaracterization, since fidgety behavior can be linked to stereotypies in neurodegenerative disease and other movement disorders. Instead, SPA should be thought of as all physical activity behavior that emanates from an unconscious drive for movement.RECENT FINDINGS: An example of this may be restless behavior, which can include fidgeting and gesticulating, frequent sit-to-stand movement, and more time spent standing and moving. All physical activity burns calories, and as such, SPA could be manipulated as a means to burn calories, and defend against weight gain and reduce excess adiposity. In this review, we discuss human and animal literature on the use of SPA in reducing weight gain, the neuromodulators that could be targeted to this end, and future directions in this field.",
keywords = "Animal, Brain, Central nervous system, DREADD, Dynorphin, Eating behavior, Exercise, Food intake, Human, Locomotion, Non-exercise energy expenditure, Obesity, Optogenetics, Orexin, Spontaneous physical activity",
author = "Kotz, {Catherine M.} and Perez-Leighton, {Claudio E.} and Teske, {Jennifer A} and Billington, {Charles J.}",
year = "2017",
month = "12",
day = "1",
doi = "10.1007/s13679-017-0288-1",
language = "English (US)",
volume = "6",
pages = "362--370",
journal = "Current obesity reports",
issn = "2162-4968",
publisher = "Springer US",
number = "4",

}

TY - JOUR

T1 - Spontaneous Physical Activity Defends Against Obesity

AU - Kotz, Catherine M.

AU - Perez-Leighton, Claudio E.

AU - Teske, Jennifer A

AU - Billington, Charles J.

PY - 2017/12/1

Y1 - 2017/12/1

N2 - PURPOSE OF REVIEW: Spontaneous physical activity (SPA) is a physical activity not motivated by a rewarding goal, such as that associated with food-seeking or wheel-running behavior. SPA is often thought of as only "fidgeting," but that is a mischaracterization, since fidgety behavior can be linked to stereotypies in neurodegenerative disease and other movement disorders. Instead, SPA should be thought of as all physical activity behavior that emanates from an unconscious drive for movement.RECENT FINDINGS: An example of this may be restless behavior, which can include fidgeting and gesticulating, frequent sit-to-stand movement, and more time spent standing and moving. All physical activity burns calories, and as such, SPA could be manipulated as a means to burn calories, and defend against weight gain and reduce excess adiposity. In this review, we discuss human and animal literature on the use of SPA in reducing weight gain, the neuromodulators that could be targeted to this end, and future directions in this field.

AB - PURPOSE OF REVIEW: Spontaneous physical activity (SPA) is a physical activity not motivated by a rewarding goal, such as that associated with food-seeking or wheel-running behavior. SPA is often thought of as only "fidgeting," but that is a mischaracterization, since fidgety behavior can be linked to stereotypies in neurodegenerative disease and other movement disorders. Instead, SPA should be thought of as all physical activity behavior that emanates from an unconscious drive for movement.RECENT FINDINGS: An example of this may be restless behavior, which can include fidgeting and gesticulating, frequent sit-to-stand movement, and more time spent standing and moving. All physical activity burns calories, and as such, SPA could be manipulated as a means to burn calories, and defend against weight gain and reduce excess adiposity. In this review, we discuss human and animal literature on the use of SPA in reducing weight gain, the neuromodulators that could be targeted to this end, and future directions in this field.

KW - Animal

KW - Brain

KW - Central nervous system

KW - DREADD

KW - Dynorphin

KW - Eating behavior

KW - Exercise

KW - Food intake

KW - Human

KW - Locomotion

KW - Non-exercise energy expenditure

KW - Obesity

KW - Optogenetics

KW - Orexin

KW - Spontaneous physical activity

UR - http://www.scopus.com/inward/record.url?scp=85049899976&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85049899976&partnerID=8YFLogxK

U2 - 10.1007/s13679-017-0288-1

DO - 10.1007/s13679-017-0288-1

M3 - Review article

VL - 6

SP - 362

EP - 370

JO - Current obesity reports

JF - Current obesity reports

SN - 2162-4968

IS - 4

ER -