(S,S)-4′′-Cyano-7,7′′-dimeth-oxy-3′, 6′-dioxodispiro-[indane-2,2′-piperazine-5′, 2′′-indane]-4-carboxamide methanol solvate: Inter-rupting the amide-to-amide hydrogen-bonded tape

Bhumasamudram Jagadish, Michael D. Carducci, Alice Dawson, Gary S. Nichol, Eugene A. Mash

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

The title methanol solvate, C24H22N4O5·CH3OH, forms an extended three-dimensional hydrogen-bonded structure, assisted by the presence of several good donor and acceptor sites. It shows none of the crystal packing features typically expected of piperazinediones, such as amide-to-amide R 2 2(8) hydrogen bonding. In this structure the methanol solvent appears to play only a space-filling role; it is not involved in any hydrogen bonding and instead is disordered over several sites. This study reports, to the best of our knowledge, the first crystal structure of an indane-containing piperazinedione compound which exhibits a three-dimensional hydrogen-bonded structure formed by classical (N - H⋯O and N - H⋯N) hydrogen-bonding inter-actions.

Original languageEnglish (US)
Pages (from-to)o431-o433
JournalActa Crystallographica Section C: Crystal Structure Communications
Volume64
Issue number8
DOIs
StatePublished - Aug 15 2008

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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