Stem cell banking for regenerative and personalized medicine

Research output: Contribution to journalReview article

18 Citations (Scopus)

Abstract

Regenerative medicine, tissue engineering and gene therapy offer the opportunity to treat and cure many of today's intractable afflictions. These approaches to personalized medicine often utilize stem cells to accomplish these goals. However, stem cells can be negatively affected by donor variables such as age and health status at the time of collection, compromising their efficacy. Stem cell banking offers the opportunity to cryogenically preserve stem cells at their most potent state for later use in these applications. Practical stem cell sources include bone marrow, umbilical cord blood and tissue, and adipose tissue. Each of these sources contains stem cells that can be obtained from most individuals, without too much difficulty and in an economical fashion. This review will discuss the advantages and disadvantages of each stem cell source, factors to be considered when contemplating banking each stem cell source, the methodology required to bank each stem cell source, and finally, current and future clinical uses of each stem cell source.

Original languageEnglish (US)
Pages (from-to)50-79
Number of pages30
JournalBiomedicines
Volume2
Issue number1
DOIs
StatePublished - Mar 1 2014

Fingerprint

Precision Medicine
Regenerative Medicine
Stem cells
Medicine
Stem Cells
Tissue
Stem Cell Factor
Gene therapy
Tissue Engineering
Cell- and Tissue-Based Therapy
Fetal Blood
Genetic Therapy
Health Status
Tissue engineering
Adipose Tissue
Bone Marrow
Bone
Blood
Health

Keywords

  • Banking
  • Cord blood
  • Cord tissue
  • MSC
  • Stem cells

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Stem cell banking for regenerative and personalized medicine. / Harris, David T.

In: Biomedicines, Vol. 2, No. 1, 01.03.2014, p. 50-79.

Research output: Contribution to journalReview article

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