Stepwise shortening of muscle fibre segments

Hendrikus "Henk" Granzier, John A. Myers, Gerald H. Pollack

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Shortening dynamics were measured in single fibres of frog skeletal muscle using a system that could track the spacing between hairs mounted on the fibre surface. Segment length changes were predominantly stepwise. The objective of the study was to identify potential artifacts and check their relevance. Several possible causes of artifactual steps were evaluated quantitatively and ruled out. In addition, the surface marker method and an independent length-detection method based on light diffraction were used simultaneously. The concurrence of results confirmed that it is highly unlikely that stepwise shortening could arise out of instrument artifact. Possible mechanisms underlying the phenomenon are considered.

Original languageEnglish (US)
Pages (from-to)242-251
Number of pages10
JournalJournal of Muscle Research and Cell Motility
Volume8
Issue number3
DOIs
StatePublished - Jun 1987
Externally publishedYes

Fingerprint

Artifacts
Muscle
Muscles
Fibers
Skeletal Muscle Fibers
Anura
Diffraction
Light

ASJC Scopus subject areas

  • Physiology
  • Endocrinology
  • Clinical Biochemistry
  • Cell Biology

Cite this

Stepwise shortening of muscle fibre segments. / Granzier, Hendrikus "Henk"; Myers, John A.; Pollack, Gerald H.

In: Journal of Muscle Research and Cell Motility, Vol. 8, No. 3, 06.1987, p. 242-251.

Research output: Contribution to journalArticle

Granzier, Hendrikus "Henk" ; Myers, John A. ; Pollack, Gerald H. / Stepwise shortening of muscle fibre segments. In: Journal of Muscle Research and Cell Motility. 1987 ; Vol. 8, No. 3. pp. 242-251.
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