The trans-terminal methyls of squalene derive from C-2 of mevalonic acid, and the conversion of squalene in turn into squalene 2,3-oxide and lanosterol occurs without interchange of isopropylidene methyls, so that C-2 of mevalonic acid provides the 4α-methyl group of lanosterol.
|Original language||English (US)|
|Number of pages||3|
|Journal||Journal of the Chemical Society D: Chemical Communications|
|State||Published - 1969|
ASJC Scopus subject areas
- Molecular Medicine