Stereoselective synthesis of all individual isomers of β-methyl-2′,6′-dimethylphenylalanine

Li Xiang, Huiwei Wu, Victor J. Hruby

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

Asymmetric synthesis of all four isomers of β-methyl-2′,6′-dimethylphenylalanine was accomplished with complete stereoselectivities and high yields by using the Evans-like auxiliary 4-phenyl-oxazolidinone as a chiral auxiliary and as a chiral resolution reagent.

Original languageEnglish (US)
Pages (from-to)83-86
Number of pages4
JournalTetrahedron: Asymmetry
Volume6
Issue number1
DOIs
StatePublished - Jan 1995

Keywords

  • Asymmetric synthesis
  • Unusual amino acids
  • β-Methyl-2′,6′-dimethylphenylalanine

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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