Structures of two new phenolic 24-nor-D:A-friedo-oleananes related to zeylasterone: A partial synthesis of trimethylzeylasterone

G. M.Kamal B. Gunaherath, A. A.Leslie Gunatilaka

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Zeylasteral and desmethylzeylasterone, two new triterpenes from Kokoona zeylanica have been shown to be 2,3-dihydroxy-6,23-dioxo-24-nor-D:A-friedo-oleana-1,3,5(10),7-tetraen-29-oic acid methyl ester (20α) and 2,3-dihydroxy-6-oxo-24-nor-D:A-friedo-oleana-1,3,5(10),7-tetraen23,29-dioic acid (20α), respectively, and have been related to trimethylzeylasterone. A partial synthesis of trimethylzeylasterone starting from pristimerin has been achieved.

Original languageEnglish (US)
Pages (from-to)2025-2028
Number of pages4
JournalTetrahedron Letters
Volume24
Issue number19
DOIs
StatePublished - 1983
Externally publishedYes

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ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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