Studies of the effects of spherulin from Coccidioides immitis on human polymorpho-nuclear leukocytes

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The effects of spherule lysate (spherulin) on human polymorphonuclear leukocyte (PMN) function was examined. PMN adherence to glass and capping was increased by spherulin, findings which may account for spherulin's interference with complement-mediated migration through cellulose ester filters. In contrast, PMN attachment to yeast, killing of bacteria, and effects on spherules were virtually unaffected by spherulin, suggesting that it does not directly inhibit PMN antimicrobial function.

Original languageEnglish (US)
Pages (from-to)107-111
Number of pages5
JournalMycopathologia
Volume90
Issue number2
DOIs
StatePublished - May 1985

Fingerprint

Coccidioides immitis
Coccidioides
neutrophils
leukocytes
Neutrophils
Leukocytes
Cellulose
Glass
glass
complement
Esters
cellulose
anti-infective agents
Yeasts
esters
yeasts
Bacteria
spherulin
bacteria

ASJC Scopus subject areas

  • Plant Science
  • Agricultural and Biological Sciences (miscellaneous)

Cite this

Studies of the effects of spherulin from Coccidioides immitis on human polymorpho-nuclear leukocytes. / Galgiani, John N.

In: Mycopathologia, Vol. 90, No. 2, 05.1985, p. 107-111.

Research output: Contribution to journalArticle

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