Studies on calcium regulation in relation to sodium potassium balance in the rabbit lens

N. A. Delamere, C. A. Paterson

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Net changes in the levels of lens calcium, magnesium, sodium, potassium, and water content were determined following exposure in vitro to iodoacetate, ouabain, lanthanum, cyanide, quercetin and cold temperature. The lens calcium content rose following inhibition of lens metabolism but did not change following specific inhibition of the sodium pump. The data revealed that regulation of the lens calcium balance is largely independent of lens sodium and potassium content. A greater increase in lens sodium content upon iodoacetate treatment vs. oubain treatment is discussed in relation to the elevation of lens calcium.

Original languageEnglish (US)
Pages (from-to)230-240
Number of pages11
JournalOphthalmic Research
Volume14
Issue number3
DOIs
StatePublished - Jan 1 1982
Externally publishedYes

Keywords

  • Calcium
  • Inhibitors
  • Ion transport
  • Rabbit lens
  • Sodium potassium

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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