Studies on the mechanism of action of salicylates vi: Effect of topical application of retinoic acid on wound‐healing retardation action of salicylic acid

K. H. Lee; Theodore G. Tong

doi:10.1002/jps.2600580633

Studies on the mechanism of action of salicylates vi: Effect of topical application of retinoic acid on wound‐healing retardation action of salicylic acid

K. H. Lee, Theodore G. Tong

Pharmacy - Administration

Research output: Contribution to journal › Article

15 Scopus citations

Abstract

Oral administration of sodium salicylate or prednisone and topical application of salicylic acid or hydrocortisone in NIB retards healing and the inhibitory action of either one of these drugs can be reversed by local application of retinoic acid. Topical application of retinol, retinyl esters, or retinoic acid alone also promotes skin wound healing in the rat.

Original language	English (US)
Pages (from-to)	773-774
Number of pages	2
Journal	Journal of pharmaceutical sciences
Volume	58
Issue number	6
DOIs	https://doi.org/10.1002/jps.2600580633
State	Published - Jun 1969

Fingerprint

Keywords

Hydrocortisone, predisone effect—wound healing
Retinoic acid effect—drug‐retarded wound healing
Salicylic acid effect—wound healing
Wound healing—tensile strength

ASJC Scopus subject areas

Pharmaceutical Science

Cite this

Lee, K. H., & Tong, T. G. (1969). Studies on the mechanism of action of salicylates vi: Effect of topical application of retinoic acid on wound‐healing retardation action of salicylic acid. Journal of pharmaceutical sciences, 58(6), 773-774. https://doi.org/10.1002/jps.2600580633

@article{be1fc537427244b2a918a4866d51aa59,

title = "Studies on the mechanism of action of salicylates vi: Effect of topical application of retinoic acid on wound‐healing retardation action of salicylic acid",

abstract = "Oral administration of sodium salicylate or prednisone and topical application of salicylic acid or hydrocortisone in NIB retards healing and the inhibitory action of either one of these drugs can be reversed by local application of retinoic acid. Topical application of retinol, retinyl esters, or retinoic acid alone also promotes skin wound healing in the rat.",

keywords = "Hydrocortisone, predisone effect—wound healing, Retinoic acid effect—drug‐retarded wound healing, Salicylic acid effect—wound healing, Wound healing—tensile strength",

author = "Lee, {K. H.} and Tong, {Theodore G.}",

year = "1969",

month = jun

doi = "10.1002/jps.2600580633",

language = "English (US)",

volume = "58",

pages = "773--774",

journal = "Journal of Pharmaceutical Sciences",

issn = "0022-3549",

publisher = "John Wiley and Sons Inc.",

number = "6",

}

TY - JOUR

T1 - Studies on the mechanism of action of salicylates vi

T2 - Effect of topical application of retinoic acid on wound‐healing retardation action of salicylic acid

AU - Lee, K. H.

AU - Tong, Theodore G.

PY - 1969/6

Y1 - 1969/6

N2 - Oral administration of sodium salicylate or prednisone and topical application of salicylic acid or hydrocortisone in NIB retards healing and the inhibitory action of either one of these drugs can be reversed by local application of retinoic acid. Topical application of retinol, retinyl esters, or retinoic acid alone also promotes skin wound healing in the rat.

AB - Oral administration of sodium salicylate or prednisone and topical application of salicylic acid or hydrocortisone in NIB retards healing and the inhibitory action of either one of these drugs can be reversed by local application of retinoic acid. Topical application of retinol, retinyl esters, or retinoic acid alone also promotes skin wound healing in the rat.

KW - Hydrocortisone, predisone effect—wound healing

KW - Retinoic acid effect—drug‐retarded wound healing

KW - Salicylic acid effect—wound healing

KW - Wound healing—tensile strength

UR - http://www.scopus.com/inward/record.url?scp=0014525353&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0014525353&partnerID=8YFLogxK

U2 - 10.1002/jps.2600580633

DO - 10.1002/jps.2600580633

M3 - Article

C2 - 5799777

AN - SCOPUS:0014525353

VL - 58

SP - 773

EP - 774

JO - Journal of Pharmaceutical Sciences

JF - Journal of Pharmaceutical Sciences

SN - 0022-3549

IS - 6

ER -

Access to Document

10.1002/jps.2600580633