Study of the radiation dose reduction capability of a CT reconstruction algorithm - LCD performance assessment using mathematical model observers

Jiahua Fan, Hsin Wu Tseng, Matthew Kupinski, Guangzhi Cao, Paavana Sainath, Jiang Hsieh

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Scopus citations

Abstract

Radiation dose on patient has become a major concern today for Computed Tomography (CT) imaging in clinical practice. Various hardware and algorithm solutions have been designed to reduce dose. Among them, iterative reconstruction (IR) has been widely expected to be an effective dose reduction approach for CT. However, there is no clear understanding on the exact amount of dose saving an IR approach can offer for various clinical applications. We know that quantitative image quality assessment should be task-based. This work applied mathematical model observers to study detectability performance of CT scan data reconstructed using an advanced IR approach as well as the conventional filtered back-projection (FBP) approach. The purpose of this work is to establish a practical and robust approach for CT IR detectability image quality evaluation and to assess the dose saving capability of the IR method under study. Low contrast (LC) objects imbedded in head size and body size phantoms were imaged multiple times with different dose levels. Independent signal present and absent pairs were generated for model observer study training and testing. Receiver Operating Characteristic (ROC) curves for location known exact and location ROC (LROC) curves for location unknown as well as their corresponding the area under the curve (AUC) values were calculated. Results showed approximately 3 times dose reduction has been achieved using the IR method under study.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2013
Subtitle of host publicationImage Perception, Observer Performance, and Technology Assessment
DOIs
StatePublished - Jun 14 2013
EventSPIE Medical Imaging Symposium 2013: Image Perception, Observer Performance, and Technology Assessment - Lake Buena Vista, FL, United States
Duration: Feb 10 2013Feb 11 2013

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume8673
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Other

OtherSPIE Medical Imaging Symposium 2013: Image Perception, Observer Performance, and Technology Assessment
CountryUnited States
CityLake Buena Vista, FL
Period2/10/132/11/13

Keywords

  • CT
  • Detection
  • Dose reduction
  • IR
  • LCD
  • Model observer

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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  • Cite this

    Fan, J., Tseng, H. W., Kupinski, M., Cao, G., Sainath, P., & Hsieh, J. (2013). Study of the radiation dose reduction capability of a CT reconstruction algorithm - LCD performance assessment using mathematical model observers. In Medical Imaging 2013: Image Perception, Observer Performance, and Technology Assessment [86731Q] (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 8673). https://doi.org/10.1117/12.2007307