Successful treatment of neuro- Behçet’s disease with infliximab

Four years follow-up

Manjinder Kaur, Emily S. Nia, Rebecca A. Millus, Dominick G. Sudano, Jeffrey R Lisse

Research output: Contribution to journalArticle

Abstract

Neuro-Behçet’s disease (NBD) is a rare but severe manifestation of Behçet’s disease. Patients with NBD tend to have high morbidity and mortality. Some patients do not respond adequately to conventional therapy (corticosteroids and immunosuppressants). This has led to treatment gaps in the therapy of NBD. There are reports in the literature of patients with Behçet’s disease responding to anti-TNF therapy. We present a case of a male patient with biopsy proven cerebral vasculitis presenting as NBD who has been in remission with near resolution of cerebral magnetic resonance imaging lesions for 4 years following treatment with infliximab and azathioprine.

Original languageEnglish (US)
Article number6115
Pages (from-to)14-16
Number of pages3
JournalRheumatology Reports
Volume7
Issue number1
DOIs
StatePublished - 2015

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Therapeutics
Central Nervous System Vasculitis
Azathioprine
Immunosuppressive Agents
Infliximab
Adrenal Cortex Hormones
Magnetic Resonance Imaging
Morbidity
Biopsy
Mortality

Keywords

  • Cerebral vasculitis
  • Immunosuppressants
  • Infliximab
  • Neuro-Behçet’s disease
  • Steroids

ASJC Scopus subject areas

  • Rheumatology
  • Immunology

Cite this

Successful treatment of neuro- Behçet’s disease with infliximab : Four years follow-up. / Kaur, Manjinder; Nia, Emily S.; Millus, Rebecca A.; Sudano, Dominick G.; Lisse, Jeffrey R.

In: Rheumatology Reports, Vol. 7, No. 1, 6115, 2015, p. 14-16.

Research output: Contribution to journalArticle

Kaur, Manjinder ; Nia, Emily S. ; Millus, Rebecca A. ; Sudano, Dominick G. ; Lisse, Jeffrey R. / Successful treatment of neuro- Behçet’s disease with infliximab : Four years follow-up. In: Rheumatology Reports. 2015 ; Vol. 7, No. 1. pp. 14-16.
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