Successful use of extracorporeal membrane oxygenation in a patient with transfusion-related acute lung injury

Jarrod Mosier, Terence O'Keeffe, Holly Graham, Peter M. Rhee

Research output: Contribution to journalReview article

Abstract

Objective: Transfusion-related acute lung injury (TRALI) is a relatively uncommon complication in patients who undergo plasma-containing blood product transfusion. Despite the cross matching process, TRALI remains the most common cause of mortality associated with transfusion. We describe a case of TRALI in a 24-year-old trauma patient who was successfully cared for on extracorporeal membrane oxygenation (ECMO). Design: Chart review. Setting: Academic medical center with Level 1 Trauma. Patients and participants: Single case from a busy urban trauma center. Interventions: Extracorporeal membrane oxygenation. Conclusion: ECMO has only rarely been successfully used in patients with TRALI; to our knowledge, ours is the first successful report of its use in a trauma patient. Its use in maintaining gas exchange in trauma patients with TRALI should be further investigated.

Original languageEnglish (US)
Pages (from-to)40-45
Number of pages6
JournalCritical Care and Shock
Volume14
Issue number2
StatePublished - Jul 11 2011

Keywords

  • Acute lung injury
  • ECMO
  • Respiratory failure
  • TRALI
  • Transfusion reaction
  • Trauma

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

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