Sugar synthesis from a gas-phase formose reaction

Abraham F. Jalbout, Leif M Abrell, Ludwik Adamowicz, Robin L Polt, A. J. Apponi, Lucy M Ziurys

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Prebiotic possibilities for the synthesis of interstellar ribose through a protic variant of the formose reaction under gas-phase conditions were studied in the absence of any known catalyst. The ion-molecule reaction products, diose and triose, were sought by mass spectrometry, and relevant masses were observed. Ab initio calculations were used to evaluate protic formose mechanism possibilities. A bilateral theoretical and experimental effort yielded a physical model for glycoaldehyde generation whereby a hydronium cation can mediate formaldehyde dimerization followed by covalent bond formation leading to those and water. These results advance the possibility that ion-molecule reactions between formaldehyde (CH2O) and H3O+ lead to formose reaction products and inform us about potential sugar formation processes in interstellar space.

Original languageEnglish (US)
Pages (from-to)433-442
Number of pages10
JournalAstrobiology
Volume7
Issue number3
DOIs
StatePublished - Jun 2007

Fingerprint

gas phase reaction
sugars
formaldehyde
reaction products
sugar
Gases
gases
vapor phases
ions
interstellar space
trioses
ribose
Formaldehyde
synthesis
dimerization
ion
physical models
covalent bonds
prebiotics
Trioses

Keywords

  • Astrobiology
  • Interstellar medium, clouds
  • Interstellar medium, molecules
  • Laboratory methods
  • Molecular processes

ASJC Scopus subject areas

  • Earth and Planetary Sciences(all)

Cite this

Sugar synthesis from a gas-phase formose reaction. / Jalbout, Abraham F.; Abrell, Leif M; Adamowicz, Ludwik; Polt, Robin L; Apponi, A. J.; Ziurys, Lucy M.

In: Astrobiology, Vol. 7, No. 3, 06.2007, p. 433-442.

Research output: Contribution to journalArticle

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