Sulci density map to aid in use of apparent diffusion coefficient for therapy evaluation

Lars A. Ewell, Christopher J. Watchman, Kurt Wharton

Research output: Contribution to journalArticle

Abstract

In order to more accurately asses variations in the apparent diffusion coefficient used for therapy evaluation, we have studied the variation in sulci density in the human brain. Sagittal, axial and coronal magnetic resonance imaging scans have been analyzed to determine the change of the coefficient of variance of pixel intensity as a function of position. In the sagittal direction, relative to the 50% most medial slices, we find an 11.0%±4.8% (S.D.) decrease in the next 25% (12.5% on each side) of the slices. The most lateral 25% of the slices had less of a decrease and more variation: 7.0%±12.2%. Similar variations were observed in axial and coronal scans.

Original languageEnglish (US)
Pages (from-to)20-25
Number of pages6
JournalMagnetic Resonance Imaging
Volume26
Issue number1
DOIs
StatePublished - Jan 1 2008

Keywords

  • Coefficient
  • Density
  • Diffusion
  • Noise
  • Sulci
  • Variation

ASJC Scopus subject areas

  • Biophysics
  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

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