Sulci density map to aid in use of apparent diffusion coefficient for therapy evaluation

Lars A. Ewell, Christopher J Watchman, Kurt Wharton

Research output: Contribution to journalArticle

Abstract

In order to more accurately asses variations in the apparent diffusion coefficient used for therapy evaluation, we have studied the variation in sulci density in the human brain. Sagittal, axial and coronal magnetic resonance imaging scans have been analyzed to determine the change of the coefficient of variance of pixel intensity as a function of position. In the sagittal direction, relative to the 50% most medial slices, we find an 11.0%±4.8% (S.D.) decrease in the next 25% (12.5% on each side) of the slices. The most lateral 25% of the slices had less of a decrease and more variation: 7.0%±12.2%. Similar variations were observed in axial and coronal scans.

Original languageEnglish (US)
Pages (from-to)20-25
Number of pages6
JournalMagnetic Resonance Imaging
Volume26
Issue number1
DOIs
StatePublished - Jan 2008

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Equidae
Magnetic resonance
therapy
Brain
diffusion coefficient
Pixels
Magnetic Resonance Imaging
Imaging techniques
evaluation
Therapeutics
brain
magnetic resonance
pixels
Direction compound
coefficients

Keywords

  • Coefficient
  • Density
  • Diffusion
  • Noise
  • Sulci
  • Variation

ASJC Scopus subject areas

  • Biophysics
  • Clinical Biochemistry
  • Structural Biology
  • Radiology Nuclear Medicine and imaging
  • Condensed Matter Physics

Cite this

Sulci density map to aid in use of apparent diffusion coefficient for therapy evaluation. / Ewell, Lars A.; Watchman, Christopher J; Wharton, Kurt.

In: Magnetic Resonance Imaging, Vol. 26, No. 1, 01.2008, p. 20-25.

Research output: Contribution to journalArticle

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