Summer syncope syndrome

Jennifer Juxiang Huang, Natasha Sharda, Irbaz Bin Riaz, Joseph S Alpert

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background Antihypertensive therapy is associated with significant relative risk reductions in the incidence of heart failure, myocardial infarction, and stroke. However, a common adverse reaction to antihypertensive therapy is orthostatic hypotension, dehydration, and syncope. We propose that continued use of antihypertensive medications at the same dosage during the dry summer months in patients living in the Sonoran desert leads to an increase in syncopal episodes. Methods All hypertensive patients who were treated with medications and admitted with International Classification of Diseases, 9th Revision code diagnosis of syncope were included. They were defined as "cases" if they presented during the summer months (May to September 2012) and "controls" if they presented during the winter months (November 2012 to March 2013). The primary outcome measure was the presence of clinical dehydration. The statistical significance was determined using the 2-sided Fisher exact test. Results A total of 496 patients with an International Classification of Diseases, 9th Revision code diagnosis of syncope were screened, and 179 patients were included in the final analysis. In patients taking antihypertensive medications, there were a significantly higher number of cases of syncope secondary to dehydration or orthostatic hypotension during the summer months (45%) compared with the winter months (26%) (P =.01). The incidence of syncope was significantly higher in older patients (63%) compared with younger individuals (37%) during the summer months. Conclusions The incidence of syncope increases during the summer months among people who reside in a dry desert climate and who are taking antihypertensive medications. On the basis of our findings, we describe an easily preventable condition that we define as the "Summer Syncope Syndrome." We recommend judicious reduction of antihypertensive therapy in patients residing in a hot and dry climate, particularly during the summer months

Original languageEnglish (US)
Pages (from-to)787-790
Number of pages4
JournalAmerican Journal of Medicine
Volume127
Issue number8
DOIs
StatePublished - 2014

Fingerprint

Syncope
Antihypertensive Agents
Dehydration
Orthostatic Hypotension
International Classification of Diseases
Desert Climate
Incidence
Risk Reduction Behavior
Climate
Therapeutics
Heart Failure
Stroke
Myocardial Infarction
Outcome Assessment (Health Care)

Keywords

  • Antihypertensive therapy
  • Desert climate
  • Summer
  • Syncope

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Summer syncope syndrome. / Huang, Jennifer Juxiang; Sharda, Natasha; Riaz, Irbaz Bin; Alpert, Joseph S.

In: American Journal of Medicine, Vol. 127, No. 8, 2014, p. 787-790.

Research output: Contribution to journalArticle

Huang, JJ, Sharda, N, Riaz, IB & Alpert, JS 2014, 'Summer syncope syndrome', American Journal of Medicine, vol. 127, no. 8, pp. 787-790. https://doi.org/10.1016/j.amjmed.2014.02.037
Huang, Jennifer Juxiang ; Sharda, Natasha ; Riaz, Irbaz Bin ; Alpert, Joseph S. / Summer syncope syndrome. In: American Journal of Medicine. 2014 ; Vol. 127, No. 8. pp. 787-790.
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abstract = "Background Antihypertensive therapy is associated with significant relative risk reductions in the incidence of heart failure, myocardial infarction, and stroke. However, a common adverse reaction to antihypertensive therapy is orthostatic hypotension, dehydration, and syncope. We propose that continued use of antihypertensive medications at the same dosage during the dry summer months in patients living in the Sonoran desert leads to an increase in syncopal episodes. Methods All hypertensive patients who were treated with medications and admitted with International Classification of Diseases, 9th Revision code diagnosis of syncope were included. They were defined as {"}cases{"} if they presented during the summer months (May to September 2012) and {"}controls{"} if they presented during the winter months (November 2012 to March 2013). The primary outcome measure was the presence of clinical dehydration. The statistical significance was determined using the 2-sided Fisher exact test. Results A total of 496 patients with an International Classification of Diseases, 9th Revision code diagnosis of syncope were screened, and 179 patients were included in the final analysis. In patients taking antihypertensive medications, there were a significantly higher number of cases of syncope secondary to dehydration or orthostatic hypotension during the summer months (45{\%}) compared with the winter months (26{\%}) (P =.01). The incidence of syncope was significantly higher in older patients (63{\%}) compared with younger individuals (37{\%}) during the summer months. Conclusions The incidence of syncope increases during the summer months among people who reside in a dry desert climate and who are taking antihypertensive medications. On the basis of our findings, we describe an easily preventable condition that we define as the {"}Summer Syncope Syndrome.{"} We recommend judicious reduction of antihypertensive therapy in patients residing in a hot and dry climate, particularly during the summer months",
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AB - Background Antihypertensive therapy is associated with significant relative risk reductions in the incidence of heart failure, myocardial infarction, and stroke. However, a common adverse reaction to antihypertensive therapy is orthostatic hypotension, dehydration, and syncope. We propose that continued use of antihypertensive medications at the same dosage during the dry summer months in patients living in the Sonoran desert leads to an increase in syncopal episodes. Methods All hypertensive patients who were treated with medications and admitted with International Classification of Diseases, 9th Revision code diagnosis of syncope were included. They were defined as "cases" if they presented during the summer months (May to September 2012) and "controls" if they presented during the winter months (November 2012 to March 2013). The primary outcome measure was the presence of clinical dehydration. The statistical significance was determined using the 2-sided Fisher exact test. Results A total of 496 patients with an International Classification of Diseases, 9th Revision code diagnosis of syncope were screened, and 179 patients were included in the final analysis. In patients taking antihypertensive medications, there were a significantly higher number of cases of syncope secondary to dehydration or orthostatic hypotension during the summer months (45%) compared with the winter months (26%) (P =.01). The incidence of syncope was significantly higher in older patients (63%) compared with younger individuals (37%) during the summer months. Conclusions The incidence of syncope increases during the summer months among people who reside in a dry desert climate and who are taking antihypertensive medications. On the basis of our findings, we describe an easily preventable condition that we define as the "Summer Syncope Syndrome." We recommend judicious reduction of antihypertensive therapy in patients residing in a hot and dry climate, particularly during the summer months

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