111In octreoscan SPECT-MRI fusion for the detection of a pancreatic insulinoma

Valeria M. Moncayo, Diego R Martin, Juan M. Sarmiento, Blazej Zbytek, Tim Fox, David M. Schuster

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A 72-year-old woman with a history of diabetes mellitus presented with severe episodes of hypoglycemia, associated with diaphoresis and somnolence, for 1 year. Workup revealed high insulin and c-peptide. Given the clinical suspicion of an insulinoma, an MRI was performed, which demonstrated abnormal enhancement in the pancreatic head. An octreotide scan with combined single-photon emission computed tomography-computed tomography was performed and fused to the MR, which identified radiotracer uptake at the site of the MR enhancement, enabling precise localization of a pancreatic somatostatin receptor-avid tumor. The patient underwent tumor enucleation with pancreatojejunostomy, and pathologic tests confirmed an insulinoma.

Original languageEnglish (US)
JournalClinical Nuclear Medicine
Volume37
Issue number3
DOIs
StatePublished - Mar 2012
Externally publishedYes

Fingerprint

Insulinoma
Single-Photon Emission-Computed Tomography
Pancreaticojejunostomy
Somatostatin Receptors
Octreotide
Hypoglycemia
Neoplasms
Diabetes Mellitus
Insulin
Peptides
pentetreotide
Single Photon Emission Computed Tomography Computed Tomography

Keywords

  • Insulinoma
  • Magnetic resonance imaging
  • Neuroendocrine tumor
  • OctreoScan

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

111In octreoscan SPECT-MRI fusion for the detection of a pancreatic insulinoma. / Moncayo, Valeria M.; Martin, Diego R; Sarmiento, Juan M.; Zbytek, Blazej; Fox, Tim; Schuster, David M.

In: Clinical Nuclear Medicine, Vol. 37, No. 3, 03.2012.

Research output: Contribution to journalArticle

Moncayo, Valeria M. ; Martin, Diego R ; Sarmiento, Juan M. ; Zbytek, Blazej ; Fox, Tim ; Schuster, David M. / 111In octreoscan SPECT-MRI fusion for the detection of a pancreatic insulinoma. In: Clinical Nuclear Medicine. 2012 ; Vol. 37, No. 3.
@article{56fa377031934cec8ac1b046a5eb7af8,
title = "111In octreoscan SPECT-MRI fusion for the detection of a pancreatic insulinoma",
abstract = "A 72-year-old woman with a history of diabetes mellitus presented with severe episodes of hypoglycemia, associated with diaphoresis and somnolence, for 1 year. Workup revealed high insulin and c-peptide. Given the clinical suspicion of an insulinoma, an MRI was performed, which demonstrated abnormal enhancement in the pancreatic head. An octreotide scan with combined single-photon emission computed tomography-computed tomography was performed and fused to the MR, which identified radiotracer uptake at the site of the MR enhancement, enabling precise localization of a pancreatic somatostatin receptor-avid tumor. The patient underwent tumor enucleation with pancreatojejunostomy, and pathologic tests confirmed an insulinoma.",
keywords = "Insulinoma, Magnetic resonance imaging, Neuroendocrine tumor, OctreoScan",
author = "Moncayo, {Valeria M.} and Martin, {Diego R} and Sarmiento, {Juan M.} and Blazej Zbytek and Tim Fox and Schuster, {David M.}",
year = "2012",
month = "3",
doi = "10.1097/RLU.0b013e31823ea402",
language = "English (US)",
volume = "37",
journal = "Clinical Nuclear Medicine",
issn = "0363-9762",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

TY - JOUR

T1 - 111In octreoscan SPECT-MRI fusion for the detection of a pancreatic insulinoma

AU - Moncayo, Valeria M.

AU - Martin, Diego R

AU - Sarmiento, Juan M.

AU - Zbytek, Blazej

AU - Fox, Tim

AU - Schuster, David M.

PY - 2012/3

Y1 - 2012/3

N2 - A 72-year-old woman with a history of diabetes mellitus presented with severe episodes of hypoglycemia, associated with diaphoresis and somnolence, for 1 year. Workup revealed high insulin and c-peptide. Given the clinical suspicion of an insulinoma, an MRI was performed, which demonstrated abnormal enhancement in the pancreatic head. An octreotide scan with combined single-photon emission computed tomography-computed tomography was performed and fused to the MR, which identified radiotracer uptake at the site of the MR enhancement, enabling precise localization of a pancreatic somatostatin receptor-avid tumor. The patient underwent tumor enucleation with pancreatojejunostomy, and pathologic tests confirmed an insulinoma.

AB - A 72-year-old woman with a history of diabetes mellitus presented with severe episodes of hypoglycemia, associated with diaphoresis and somnolence, for 1 year. Workup revealed high insulin and c-peptide. Given the clinical suspicion of an insulinoma, an MRI was performed, which demonstrated abnormal enhancement in the pancreatic head. An octreotide scan with combined single-photon emission computed tomography-computed tomography was performed and fused to the MR, which identified radiotracer uptake at the site of the MR enhancement, enabling precise localization of a pancreatic somatostatin receptor-avid tumor. The patient underwent tumor enucleation with pancreatojejunostomy, and pathologic tests confirmed an insulinoma.

KW - Insulinoma

KW - Magnetic resonance imaging

KW - Neuroendocrine tumor

KW - OctreoScan

UR - http://www.scopus.com/inward/record.url?scp=84857200896&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84857200896&partnerID=8YFLogxK

U2 - 10.1097/RLU.0b013e31823ea402

DO - 10.1097/RLU.0b013e31823ea402

M3 - Article

VL - 37

JO - Clinical Nuclear Medicine

JF - Clinical Nuclear Medicine

SN - 0363-9762

IS - 3

ER -