@article{526f9ef8932a4d9eb25c547d5c3d1b78,
title = "Superficial femoral artery thrombosis as a cause for distal embolism in primary antiphospholipid syndrome",
abstract = "Antiphospholipid syndrome is a diagnosis with the clinical manifestations of thromboses in the presence of an antiphospholipid antibody. A 25-year-old man with a history of deep venous thrombosis, pulmonary emboli, and myocardial infarction, and receiving long-term anticoagulation with warfarin, all due to primary antiphospholipid syndrome, presented with blue toe syndrome from a primary superficial femoral artery thrombus. He was anticoagulated with fondaparinux in addition to dipyridamole and aspirin perioperatively. The area of thrombus was resected and reconstructed using a cephalic vein interposition graft. This report reviews antiphospholipid syndrome and identifies potential questions and problems relating to a rare clinical presentation.",
author = "Lauvao, {Lannery S.} and Goshima, {Kaoru R.} and Leon, {Luis R.} and Nolan, {Paul E.} and Hughes, {John D.}",
note = "Funding Information: We recognize that sometimes it is difficult to differentiate an embolus from primary thrombosis, especially in absence of classic findings of atherosclerotic disease and cardiac arrhythmia. Our conclusion for APS thrombosis was supported by our in situ evaluation of the grossly abnormal vessel and the pathologist's final description and conclusion. The femoral thrombus was adherent to the vessel wall and recanalization had occurred to suggest it was chronic. Our negative cardiac source workup and angiographic imaging further suggests primary thrombosis. The occluded IVCF also makes it unlikely for a lower extremity DVT paradoxic embolic event to have occurred. To our knowledge, our report represents a rare case of distal embolization caused by isolated SFA thrombosis in a patient diagnosed with primary APS. ",
year = "2008",
month = aug,
doi = "10.1016/j.jvs.2008.02.052",
language = "English (US)",
volume = "48",
pages = "472--477",
journal = "Journal of Vascular Surgery",
issn = "0741-5214",
publisher = "Mosby Inc.",
number = "2",
}