Abstract
Surgical probes used in nuclear medicine can be maneuvered close to a suspected tumor site, thereby achieving higher resolution and sensitivity than external gamma cameras. Tomography with handheld probes is not possible, however, so it is difficult to determine whether an increase in the photon count rate is caused by features near the probe or by variations in the distant background radiation. Our group has experimented with several probe designs that address this problem. This paper describes a probe that images nearby objects without a collimator, and which is insensitive to inhomogeneities in the distant background level. The probe, which is used with a radionuclide that emits multiple photons per decay, such as 111 In, consists of a collimatorless array of gamma-ray detectors connected by coincidence circuitry. We used a Monte Carlo routine to simulate data collection from such a system and reconstructed the images using the pseudoinverse obtained by singular value decomposition. The images show a significant suppression of distant sources when compared to a probe equipped with a conventional parallel-hole collimator.
Original language | English (US) |
---|---|
Pages (from-to) | 333-341 |
Number of pages | 9 |
Journal | Image and Vision Computing |
Volume | 10 |
Issue number | 6 |
DOIs | |
State | Published - 1992 |
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Keywords
- gamma rays
- Monte Carlo
- nuclear medicine
- singular value decomposition (SVD)
- surgical probes
ASJC Scopus subject areas
- Computer Vision and Pattern Recognition
- Signal Processing
- Electrical and Electronic Engineering
Cite this
Surgical probe design for a coincidence imaging system without a collimator. / Saffer, J. R.; Barrett, Harrison H; Barber, H. B.; Woolfenden, J. M.
In: Image and Vision Computing, Vol. 10, No. 6, 1992, p. 333-341.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Surgical probe design for a coincidence imaging system without a collimator
AU - Saffer, J. R.
AU - Barrett, Harrison H
AU - Barber, H. B.
AU - Woolfenden, J. M.
PY - 1992
Y1 - 1992
N2 - Surgical probes used in nuclear medicine can be maneuvered close to a suspected tumor site, thereby achieving higher resolution and sensitivity than external gamma cameras. Tomography with handheld probes is not possible, however, so it is difficult to determine whether an increase in the photon count rate is caused by features near the probe or by variations in the distant background radiation. Our group has experimented with several probe designs that address this problem. This paper describes a probe that images nearby objects without a collimator, and which is insensitive to inhomogeneities in the distant background level. The probe, which is used with a radionuclide that emits multiple photons per decay, such as 111 In, consists of a collimatorless array of gamma-ray detectors connected by coincidence circuitry. We used a Monte Carlo routine to simulate data collection from such a system and reconstructed the images using the pseudoinverse obtained by singular value decomposition. The images show a significant suppression of distant sources when compared to a probe equipped with a conventional parallel-hole collimator.
AB - Surgical probes used in nuclear medicine can be maneuvered close to a suspected tumor site, thereby achieving higher resolution and sensitivity than external gamma cameras. Tomography with handheld probes is not possible, however, so it is difficult to determine whether an increase in the photon count rate is caused by features near the probe or by variations in the distant background radiation. Our group has experimented with several probe designs that address this problem. This paper describes a probe that images nearby objects without a collimator, and which is insensitive to inhomogeneities in the distant background level. The probe, which is used with a radionuclide that emits multiple photons per decay, such as 111 In, consists of a collimatorless array of gamma-ray detectors connected by coincidence circuitry. We used a Monte Carlo routine to simulate data collection from such a system and reconstructed the images using the pseudoinverse obtained by singular value decomposition. The images show a significant suppression of distant sources when compared to a probe equipped with a conventional parallel-hole collimator.
KW - gamma rays
KW - Monte Carlo
KW - nuclear medicine
KW - singular value decomposition (SVD)
KW - surgical probes
UR - http://www.scopus.com/inward/record.url?scp=38249013105&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=38249013105&partnerID=8YFLogxK
U2 - 10.1016/0262-8856(92)90019-Y
DO - 10.1016/0262-8856(92)90019-Y
M3 - Article
AN - SCOPUS:38249013105
VL - 10
SP - 333
EP - 341
JO - Image and Vision Computing
JF - Image and Vision Computing
SN - 0262-8856
IS - 6
ER -