Surgical probe design for a coincidence imaging system without a collimator

J. R. Saffer, Harrison H Barrett, H. B. Barber, J. M. Woolfenden

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

Surgical probes used in nuclear medicine can be maneuvered close to a suspected tumor site, thereby achieving higher resolution and sensitivity than external gamma cameras. Tomography with handheld probes is not possible, however, so it is difficult to determine whether an increase in the photon count rate is caused by features near the probe or by variations in the distant background radiation. Our group has experimented with several probe designs that address this problem. This paper describes a probe that images nearby objects without a collimator and is insensitive to inhomogeneities in the distant background level. The probe, which is used with a radionuclide that emits multiple photons per decay, such as 111In, consists of a collimatorless array of gamma-ray detectors connected by coincidence circuitry. We used a Monte Carlo routine to simulate data collection from such a system and reconstructed the images using the pseudoinverse obtained by singular value decomposition (SVD). The images show a significant suppression of distant sources when compared to a probe equipped with a conventional parallel-hole collimator.

Original languageEnglish (US)
Title of host publicationInformation Processing in Medical Imaging - 12th International Conference, IPMI 1991, Proceedings
PublisherSpringer Verlag
Pages9-22
Number of pages14
Volume511 LNCS
ISBN (Print)9783540542469
DOIs
StatePublished - 1991
Event12th International Conference on Information Processing in Medical Imaging, IPMI 1991 - Wye, United Kingdom
Duration: Jul 7 1991Jul 12 1991

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume511 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Other

Other12th International Conference on Information Processing in Medical Imaging, IPMI 1991
CountryUnited Kingdom
CityWye
Period7/7/917/12/91

Keywords

  • Gamma rays
  • Monte carlo
  • Nuclear medicine
  • Singular value decomposition (SVD)
  • Surgical probes

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

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  • Cite this

    Saffer, J. R., Barrett, H. H., Barber, H. B., & Woolfenden, J. M. (1991). Surgical probe design for a coincidence imaging system without a collimator. In Information Processing in Medical Imaging - 12th International Conference, IPMI 1991, Proceedings (Vol. 511 LNCS, pp. 9-22). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 511 LNCS). Springer Verlag. https://doi.org/10.1007/BFb0033738