Survival after intravenous thrombin prior to cardiopulmonary bypass

Vance G Nielsen, Samata R Paidy, Camron A. Meek, Tiffany K. Thornton, Scott D Lick

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We present a case of a patient undergoing aortic valve replacement being inadvertently administered 5000 U of bovine thrombin instead of heparin for anticoagulation for cardiopulmonary bypass. The labeling error was made within the operating room pharmacy. The key to survival of this patient was a rapid diagnosis, administration of antithrombin and heparin, and removal of cardiac and great vessel thrombi. It is recommended that point of care anesthesia providers `prepare heparin for cardiopulmonary bypass anticoagulation, as thrombin is not used in anesthetic practice and is not contained within anesthesia cabinet medication drawers.

Original languageEnglish (US)
Pages (from-to)485-487
Number of pages3
JournalInternational Journal of Legal Medicine
Volume131
Issue number2
DOIs
StatePublished - Mar 1 2017

Fingerprint

Cardiopulmonary Bypass
Thrombin
Heparin
Survival
Anesthesia
Point-of-Care Systems
Antithrombins
Operating Rooms
Aortic Valve
Anesthetics
Thrombosis

Keywords

  • Antithrombin
  • Cardiopulmonary bypass
  • Heparin
  • Medication error
  • Thrombin

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Survival after intravenous thrombin prior to cardiopulmonary bypass. / Nielsen, Vance G; Paidy, Samata R; Meek, Camron A.; Thornton, Tiffany K.; Lick, Scott D.

In: International Journal of Legal Medicine, Vol. 131, No. 2, 01.03.2017, p. 485-487.

Research output: Contribution to journalArticle

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