Synergetic roles of TGF-β signaling in tissue engineering

Eun A. Kwak, Nam Y. Lee

Research output: Contribution to journalReview article

2 Scopus citations

Abstract

Recent advances in tissue engineering highlight biomaterial designs with context-specific growth factors, cytokines and various small molecules to better mimic the natural extracellular matrix (ECM) microenvironments. These efforts have led to direct improvements in cell-cell and cell-ECM interactions while mitigating undesirable cellular and immunogenic responses. In this short review, we focus on the crucial roles and regulation of transforming growth factor β (TGF-β) signaling in biomaterial applications during tissue repair and regeneration.

Original languageEnglish (US)
Pages (from-to)60-63
Number of pages4
JournalCytokine
Volume115
DOIs
StatePublished - Mar 2019

Keywords

  • Biomaterials
  • Inflammation
  • Regenerative medicine
  • TGF beta
  • Tissue engineering

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Biochemistry
  • Hematology
  • Molecular Biology

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