@article{927f0f6c7263445ca3282f8256eb22a7,
title = "Synthesis and biological activities of flavolipids",
abstract = "Syntheses of the bacterial surfactants 6S,6S-, 9S,9S-, and 9U,9U-flavolipids confirmed the structures proposed for them from spectroscopic analysis of a flavolipid mixture and made pure flavolipids available for the first time. All three synthetic flavolipids and a straight chain analogue were found to be weakly cytotoxic and to inhibit metastatic cancer cell migration, with 9U,9U-flavolipid (the most abundant natural flavolipid) having the most activity. Biosynthetic routes to the branched side-chains of the flavolipids are suggested, and it is proposed that branched chains are employed to hinder biodegradation.",
keywords = "Biosurfactant, Flavobacterium, Flavolipid, Siderophore",
author = "Ahad, {Samiul M.} and Ange, {Alison L.} and Bates, {Robert B.} and Bell, {Bonnie L.} and Bodour, {Adria A.} and Bourne, {Bryan R.} and Contreras, {Cristina G.} and Goldberg, {Emily L.} and Gunatilaka, {A. A.Leslie} and Sheryl King and Lee, {Albert K.} and Low, {Rebecca L.} and Maier, {Raina M.} and Marlor, {Kathryn M.} and Marron, {Marilyn T.} and Scolnik, {Ryan C.} and Streeter, {Matthew J.} and Malgorzata Strelczuk and Trinh, {Long N.} and Truong, {Vu K.} and Vissering, {Sage P.} and Weick, {Megan C.} and Williams, {Maria T.}",
note = "Funding Information: This work was supported by grant number 0714245 from the National Science Foundation and by a Camille and Henry Dreyfus Foundation Senior Scientist Mentor Initiative Award to R.B.B. Copyright: Copyright 2011 Elsevier B.V., All rights reserved.",
year = "2010",
month = nov,
day = "20",
doi = "10.1016/j.tet.2010.09.088",
language = "English (US)",
volume = "66",
pages = "9107--9112",
journal = "Tetrahedron",
issn = "0040-4020",
publisher = "Elsevier Limited",
number = "47",
}