Synthesis of carbohydrate-based antibiotics

Chi Huey Wong, Marian C. Bryan, Paul T. Nyffeler, Haitian Liu, Eli Chapman

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

Tackling the problem of carbohydrate recognition is a subject of current interest. Our strategies in this regard include development of new methods for the synthesis of saccharides and sugar arrays for screening, design of D-peptides to target bacterial cell-surface sugars, preparation of mechanism-based inhibitors of the enzymes involved in the biosynthesis of saccharides and the synthesis of aminoglycoside mimetics to target RNA.

Original languageEnglish (US)
Pages (from-to)179-186
Number of pages8
JournalPure and Applied Chemistry
Volume75
Issue number2-3
DOIs
StatePublished - Jan 1 2003
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

Fingerprint Dive into the research topics of 'Synthesis of carbohydrate-based antibiotics'. Together they form a unique fingerprint.

  • Cite this

    Wong, C. H., Bryan, M. C., Nyffeler, P. T., Liu, H., & Chapman, E. (2003). Synthesis of carbohydrate-based antibiotics. Pure and Applied Chemistry, 75(2-3), 179-186. https://doi.org/10.1351/pac200375020179