Synthesis of carbohydrate-based antibiotics

Chi Huey Wong, Marian C. Bryan, Paul T. Nyffeler, Haitian Liu, Eli Chapman

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

Tackling the problem of carbohydrate recognition is a subject of current interest. Our strategies in this regard include development of new methods for the synthesis of saccharides and sugar arrays for screening, design of D-peptides to target bacterial cell-surface sugars, preparation of mechanism-based inhibitors of the enzymes involved in the biosynthesis of saccharides and the synthesis of aminoglycoside mimetics to target RNA.

Original languageEnglish (US)
Pages (from-to)179-186
Number of pages8
JournalPure and Applied Chemistry
Volume75
Issue number2-3
DOIs
StatePublished - 2003
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

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