Synthesis of DNA oligomers possessing a covalently cross-linked Watson - Crick base pair model

Hong Yu Li, Yao Ling Qiu, Elisabeth Moyroud, Yoshito Kishi

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Building bridges: A feasible solidphase synthesis of antiparallel n-, h-, and H-type DNA oligomers (see picture) has been demonstrated. The oligomers possess a CH2-bridged base-pair model that should be conformationally flexible, even after base pairing.

Original languageEnglish (US)
Pages (from-to)1471-1475
Number of pages5
JournalAngewandte Chemie - International Edition
Volume40
Issue number8
DOIs
StatePublished - Apr 17 2001
Externally publishedYes

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Oligomers
DNA
triplex DNA

Keywords

  • Nucleosides
  • Nucleotides
  • Oligonucleotides
  • Solid-phase synthesis
  • Watson-Crick base pairs

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

Cite this

Synthesis of DNA oligomers possessing a covalently cross-linked Watson - Crick base pair model. / Li, Hong Yu; Qiu, Yao Ling; Moyroud, Elisabeth; Kishi, Yoshito.

In: Angewandte Chemie - International Edition, Vol. 40, No. 8, 17.04.2001, p. 1471-1475.

Research output: Contribution to journalArticle

Li, Hong Yu ; Qiu, Yao Ling ; Moyroud, Elisabeth ; Kishi, Yoshito. / Synthesis of DNA oligomers possessing a covalently cross-linked Watson - Crick base pair model. In: Angewandte Chemie - International Edition. 2001 ; Vol. 40, No. 8. pp. 1471-1475.
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