Synthesis of [14C]-imexon

Bhumasamudram Jagadish, Bhashyam S. Iyengar, Anikó M. Sólyom, William A. Remers, Robert T. Dorr, Jason Shin Yu, Surendra Gupta, Eugene A. Mash

Research output: Contribution to journalArticle

3 Scopus citations


A four-step synthesis of [14C]-imexon is described, starting from [14C]-phosgene. The overall yield is 27% and the specific activity is 55 mCi/mmol.

Original languageEnglish (US)
Pages (from-to)165-170
Number of pages6
JournalJournal of Labelled Compounds and Radiopharmaceuticals
Issue number3
StatePublished - Mar 1 2005


  • Anticancer agent
  • Aziridine
  • Imexon
  • Sulfhydryl-binding

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Radiology Nuclear Medicine and imaging
  • Drug Discovery
  • Spectroscopy
  • Organic Chemistry

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  • Cite this

    Jagadish, B., Iyengar, B. S., Sólyom, A. M., Remers, W. A., Dorr, R. T., Yu, J. S., Gupta, S., & Mash, E. A. (2005). Synthesis of [14C]-imexon. Journal of Labelled Compounds and Radiopharmaceuticals, 48(3), 165-170.