System Integration - A Major Step toward Lab on a Chip

Mandy L.Y. Sin, Jian Gao, Joseph C. Liao, Pak K. Wong

Research output: Contribution to journalReview article

64 Scopus citations

Abstract

Microfluidics holds great promise to revolutionize various areas of biological engineering, such as single cell analysis, environmental monitoring, regenerative medicine, and point-of-care diagnostics. Despite the fact that intensive efforts have been devoted into the field in the past decades, microfluidics has not yet been adopted widely. It is increasingly realized that an effective system integration strategy that is low cost and broadly applicable to various biological engineering situations is required to fully realize the potential of microfluidics. In this article, we review several promising system integration approaches for microfluidics and discuss their advantages, limitations, and applications. Future advancements of these microfluidic strategies will lead toward translational lab-on-a-chip systems for a wide spectrum of biological engineering applications.

Original languageEnglish (US)
Article number6
JournalJournal of Biological Engineering
Volume5
DOIs
StatePublished - May 25 2011

ASJC Scopus subject areas

  • Environmental Engineering
  • Biomedical Engineering
  • Molecular Biology
  • Cell Biology

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