Abstract
We have developed a preclinical rabbit cardiac SPECT system by re-engineering a classical clinical SPECT scanner with state-of-the-art electronics and control systems. Notable features include digital waveform capture of the time-dependent outputs of the photomultiplier tubes (PMT). The digitization of the scintillation pulses allows for the incorporation of the entire waveform into the maximum-likelihood estimation (MLE) of event parameters (x, y, energy, etc.), rather than one scalar (i.e. integrated current). We present here details of the waveform-inclusive MLE, the measurements of the mean-detector-response functions, and the determination of the point spread function, along with the associated acceleration via graphics-processor-unit (GPU) programming. Additionally, calibration algorithms of the system are discussed.
Original language | English (US) |
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Title of host publication | Radiation Detectors in Medicine, Industry, and National Security XIX |
Editors | H. Bradford Barber, Lars R. Furenlid, Gary P. Grim |
Publisher | SPIE |
Volume | 10763 |
ISBN (Electronic) | 9781510620971 |
DOIs | |
State | Published - Jan 1 2018 |
Event | Radiation Detectors in Medicine, Industry, and National Security XIX 2018 - San Diego, United States Duration: Aug 22 2018 → Aug 23 2018 |
Other
Other | Radiation Detectors in Medicine, Industry, and National Security XIX 2018 |
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Country | United States |
City | San Diego |
Period | 8/22/18 → 8/23/18 |
Keywords
- Photon Processing
- Preclinical SPECT
- SPECT
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Computer Science Applications
- Applied Mathematics
- Electrical and Electronic Engineering