Template-guided stereotactic implantation of malignant brain tumors for interstitial thermoradiotherapy

R. P. Iacono, Baldassarre Stea, B. A. Lulu, T. Cetas, J. R. Cassady

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

A phase I trial of 25 patients with anaplastic astrocytoma or glioblastoma multiforme is described. Hyperthermia and radiation were delivered stereotactically by means of template-guided interstitial catheters loaded with ferromagnetic wires and then 192Ir seeds. Implant volumes ranged from 15 to 113 ml (mean 54 ml) involving 9-38 catheters (mean 18); parallel catheters used hexagonal spacing of 1.0-1.5 cm. Patient tolerance of these procedures was excellent. Postoperative morbidity due to additional mass effect or edema was low, but there has been one death and one complication of hydrocephalus, bleeding and symptomatic pneumocephalus, each.

Original languageEnglish (US)
Pages (from-to)199-204
Number of pages6
JournalStereotactic and Functional Neurosurgery
Volume59
Issue number1-4
DOIs
StatePublished - 1992

Fingerprint

Brain Neoplasms
Catheters
Pneumocephalus
Astrocytoma
Glioblastoma
Hydrocephalus
Edema
Seeds
Fever
Radiation
Hemorrhage
Morbidity

Keywords

  • brachytherapy
  • hyperthermia
  • stereotactic surgery

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Template-guided stereotactic implantation of malignant brain tumors for interstitial thermoradiotherapy. / Iacono, R. P.; Stea, Baldassarre; Lulu, B. A.; Cetas, T.; Cassady, J. R.

In: Stereotactic and Functional Neurosurgery, Vol. 59, No. 1-4, 1992, p. 199-204.

Research output: Contribution to journalArticle

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