The cardiometabolic syndrome as a cardiovascular risk factor

Gurushankar Govindarajan, Adam Whaley-Connell, Maryann Mugo, Craig S Stump, James R. Sowers

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

The cardiometabolic syndrome (CMS) is associated with cardiovascular disease (CVD) and includes a constellation of risk factors such as central obesity, hypertension, insulin resistance, dyslipidemia, microalbuminuria, and hypercoagulability. Collectively, these risk factors increase CVD endpoints such as stroke, congestive heart failure, chronic kidney disease (CKD), and overall mortality. The CMS is associated with endothelial dysfunction, inflammation, abnormal thrombolysis, and increased oxidative stress that accentuate progression of CVD. We will review how the varying components of the CMS relate to an increased CVD and renal disease risk.

Original languageEnglish (US)
Pages (from-to)311-318
Number of pages8
JournalAmerican Journal of the Medical Sciences
Volume330
Issue number6
StatePublished - Dec 2005
Externally publishedYes

Fingerprint

Cardiovascular Diseases
Thrombophilia
Abdominal Obesity
Dyslipidemias
Chronic Renal Insufficiency
Insulin Resistance
Oxidative Stress
Heart Failure
Stroke
Hypertension
Inflammation
Kidney
Mortality

Keywords

  • Cardiometabolic syndrome
  • Endothelial dysfunction
  • Hypertension
  • Microalbuminuria
  • Obesity

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Govindarajan, G., Whaley-Connell, A., Mugo, M., Stump, C. S., & Sowers, J. R. (2005). The cardiometabolic syndrome as a cardiovascular risk factor. American Journal of the Medical Sciences, 330(6), 311-318.

The cardiometabolic syndrome as a cardiovascular risk factor. / Govindarajan, Gurushankar; Whaley-Connell, Adam; Mugo, Maryann; Stump, Craig S; Sowers, James R.

In: American Journal of the Medical Sciences, Vol. 330, No. 6, 12.2005, p. 311-318.

Research output: Contribution to journalArticle

Govindarajan, G, Whaley-Connell, A, Mugo, M, Stump, CS & Sowers, JR 2005, 'The cardiometabolic syndrome as a cardiovascular risk factor', American Journal of the Medical Sciences, vol. 330, no. 6, pp. 311-318.
Govindarajan G, Whaley-Connell A, Mugo M, Stump CS, Sowers JR. The cardiometabolic syndrome as a cardiovascular risk factor. American Journal of the Medical Sciences. 2005 Dec;330(6):311-318.
Govindarajan, Gurushankar ; Whaley-Connell, Adam ; Mugo, Maryann ; Stump, Craig S ; Sowers, James R. / The cardiometabolic syndrome as a cardiovascular risk factor. In: American Journal of the Medical Sciences. 2005 ; Vol. 330, No. 6. pp. 311-318.
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