The coaction of tonic and phasic dopamine dynamics

Christopher W. Atcherley, Kevin M. Wood, Kate L. Parent, Parastoo Hashemi, Michael L. Heien

Research output: Contribution to journalArticle

32 Scopus citations

Abstract

Tonic neurochemical dopamine activity underlies many brain functions; however a consensus on this important concentration has not yet been reached. In this work, we introduce in vivo fast-scan controlled-adsorption voltammetry to report tonic dopamine concentrations (90 ± 9 nM) and the dopamine diffusion coefficient (1.05 ± 0.09 × 10-6 cm2 s-1) in the mouse brain.

Original languageEnglish (US)
Pages (from-to)2235-2238
Number of pages4
JournalChemical Communications
Volume51
Issue number12
DOIs
StatePublished - Feb 11 2015

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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  • Cite this

    Atcherley, C. W., Wood, K. M., Parent, K. L., Hashemi, P., & Heien, M. L. (2015). The coaction of tonic and phasic dopamine dynamics. Chemical Communications, 51(12), 2235-2238. https://doi.org/10.1039/c4cc06165a