The "conscious pilot"-dendritic synchrony moves through the brain to mediate consciousness

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

Cognitive brain functions including sensory processing and control of behavior are understood as "neurocomputation" in axonal-dendritic synaptic networks of "integrate-and-fire" neurons. Cognitive neurocomputation with consciousness is accompanied by 30- to 90-Hz gamma synchrony electroencephalography (EEG), and non-conscious neurocomputation is not. Gamma synchrony EEG derives largely from neuronal groups linked by dendritic-dendritic gap junctions, forming transient syncytia ("dendritic webs") in input/integration layers oriented sideways to axonal-dendritic neurocomputational flow. As gap junctions open and close, a gamma-synchronized dendritic web can rapidly change topology and move through the brain as a spatiotemporal envelope performing collective integration and volitional choices correlating with consciousness. The "conscious pilot" is a metaphorical description for a mobile gamma-synchronized dendritic web as vehicle for a conscious agent/pilot which experiences and assumes control of otherwise non-conscious auto-pilot neurocomputation.

Original languageEnglish (US)
Pages (from-to)71-93
Number of pages23
JournalJournal of Biological Physics
Volume36
Issue number1
DOIs
StatePublished - Jan 2010

Fingerprint

consciousness
Gap Junctions
Consciousness
brain
Electroencephalography
electroencephalography
Behavior Control
Brain
Giant Cells
Cognition
neurons
Neurons
vehicles
envelopes
topology
Pilots

Keywords

  • Action potentials
  • Brain
  • Cognition
  • Computer worm
  • Connexin
  • Consciousness
  • Dendrites
  • EEG
  • Electroencephalography
  • Gamma synchrony
  • Gap junctions
  • Integrate and fire
  • Integration
  • NCC
  • Neural correlate of consciousness
  • Neural networks
  • Neuron
  • Spikes
  • Volition

ASJC Scopus subject areas

  • Biophysics
  • Cell Biology
  • Molecular Biology
  • Atomic and Molecular Physics, and Optics

Cite this

The "conscious pilot"-dendritic synchrony moves through the brain to mediate consciousness. / Hameroff, Stuart R.

In: Journal of Biological Physics, Vol. 36, No. 1, 01.2010, p. 71-93.

Research output: Contribution to journalArticle

@article{e03c7e589cea4ef8b7d38d8cc79793de,
title = "The {"}conscious pilot{"}-dendritic synchrony moves through the brain to mediate consciousness",
abstract = "Cognitive brain functions including sensory processing and control of behavior are understood as {"}neurocomputation{"} in axonal-dendritic synaptic networks of {"}integrate-and-fire{"} neurons. Cognitive neurocomputation with consciousness is accompanied by 30- to 90-Hz gamma synchrony electroencephalography (EEG), and non-conscious neurocomputation is not. Gamma synchrony EEG derives largely from neuronal groups linked by dendritic-dendritic gap junctions, forming transient syncytia ({"}dendritic webs{"}) in input/integration layers oriented sideways to axonal-dendritic neurocomputational flow. As gap junctions open and close, a gamma-synchronized dendritic web can rapidly change topology and move through the brain as a spatiotemporal envelope performing collective integration and volitional choices correlating with consciousness. The {"}conscious pilot{"} is a metaphorical description for a mobile gamma-synchronized dendritic web as vehicle for a conscious agent/pilot which experiences and assumes control of otherwise non-conscious auto-pilot neurocomputation.",
keywords = "Action potentials, Brain, Cognition, Computer worm, Connexin, Consciousness, Dendrites, EEG, Electroencephalography, Gamma synchrony, Gap junctions, Integrate and fire, Integration, NCC, Neural correlate of consciousness, Neural networks, Neuron, Spikes, Volition",
author = "Hameroff, {Stuart R}",
year = "2010",
month = "1",
doi = "10.1007/s10867-009-9148-x",
language = "English (US)",
volume = "36",
pages = "71--93",
journal = "Journal of Biological Physics",
issn = "0092-0606",
publisher = "Springer Netherlands",
number = "1",

}

TY - JOUR

T1 - The "conscious pilot"-dendritic synchrony moves through the brain to mediate consciousness

AU - Hameroff, Stuart R

PY - 2010/1

Y1 - 2010/1

N2 - Cognitive brain functions including sensory processing and control of behavior are understood as "neurocomputation" in axonal-dendritic synaptic networks of "integrate-and-fire" neurons. Cognitive neurocomputation with consciousness is accompanied by 30- to 90-Hz gamma synchrony electroencephalography (EEG), and non-conscious neurocomputation is not. Gamma synchrony EEG derives largely from neuronal groups linked by dendritic-dendritic gap junctions, forming transient syncytia ("dendritic webs") in input/integration layers oriented sideways to axonal-dendritic neurocomputational flow. As gap junctions open and close, a gamma-synchronized dendritic web can rapidly change topology and move through the brain as a spatiotemporal envelope performing collective integration and volitional choices correlating with consciousness. The "conscious pilot" is a metaphorical description for a mobile gamma-synchronized dendritic web as vehicle for a conscious agent/pilot which experiences and assumes control of otherwise non-conscious auto-pilot neurocomputation.

AB - Cognitive brain functions including sensory processing and control of behavior are understood as "neurocomputation" in axonal-dendritic synaptic networks of "integrate-and-fire" neurons. Cognitive neurocomputation with consciousness is accompanied by 30- to 90-Hz gamma synchrony electroencephalography (EEG), and non-conscious neurocomputation is not. Gamma synchrony EEG derives largely from neuronal groups linked by dendritic-dendritic gap junctions, forming transient syncytia ("dendritic webs") in input/integration layers oriented sideways to axonal-dendritic neurocomputational flow. As gap junctions open and close, a gamma-synchronized dendritic web can rapidly change topology and move through the brain as a spatiotemporal envelope performing collective integration and volitional choices correlating with consciousness. The "conscious pilot" is a metaphorical description for a mobile gamma-synchronized dendritic web as vehicle for a conscious agent/pilot which experiences and assumes control of otherwise non-conscious auto-pilot neurocomputation.

KW - Action potentials

KW - Brain

KW - Cognition

KW - Computer worm

KW - Connexin

KW - Consciousness

KW - Dendrites

KW - EEG

KW - Electroencephalography

KW - Gamma synchrony

KW - Gap junctions

KW - Integrate and fire

KW - Integration

KW - NCC

KW - Neural correlate of consciousness

KW - Neural networks

KW - Neuron

KW - Spikes

KW - Volition

UR - http://www.scopus.com/inward/record.url?scp=73449119625&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=73449119625&partnerID=8YFLogxK

U2 - 10.1007/s10867-009-9148-x

DO - 10.1007/s10867-009-9148-x

M3 - Article

VL - 36

SP - 71

EP - 93

JO - Journal of Biological Physics

JF - Journal of Biological Physics

SN - 0092-0606

IS - 1

ER -