TY - JOUR
T1 - The development of crustacean limbs and the evolution of arthropods
AU - Panganiban, Grace
AU - Sebring, Angela
AU - Nagy, Lisa
AU - Carroll, Sean
PY - 1995/1/1
Y1 - 1995/1/1
N2 - Arthropods exhibit great diversity in the position, number, morphology, and function of their limbs. The evolutionary relations among limb types and among the arthropod groups that bear them (insects, crustaceans, myriapods, and chelicerates) are controversial. Here, the use of molecular probes, including an antibody to proteins encoded by arthropod and vertebrate Distal-less (Dll and Dlx) genes, provided evidence that common genetic mechanisms underlie the development of all arthropod limbs and their branches and that all arthropods derive from a common ancestor. However, differences between crustacean and insect body plans were found to correlate with differences in the deployment of particular homeotic genes and in the ways that these genes regulate limb development.
AB - Arthropods exhibit great diversity in the position, number, morphology, and function of their limbs. The evolutionary relations among limb types and among the arthropod groups that bear them (insects, crustaceans, myriapods, and chelicerates) are controversial. Here, the use of molecular probes, including an antibody to proteins encoded by arthropod and vertebrate Distal-less (Dll and Dlx) genes, provided evidence that common genetic mechanisms underlie the development of all arthropod limbs and their branches and that all arthropods derive from a common ancestor. However, differences between crustacean and insect body plans were found to correlate with differences in the deployment of particular homeotic genes and in the ways that these genes regulate limb development.
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U2 - 10.1126/science.270.5240.1363
DO - 10.1126/science.270.5240.1363
M3 - Article
C2 - 7481825
AN - SCOPUS:0028973487
VL - 270
SP - 1363
EP - 1366
JO - Science
JF - Science
SN - 0036-8075
IS - 5240
ER -