The effect of β-adrenergic stimulation on the bladder and urethra following radical hysterectomy

R. H J Kerr-Wilson, J. W. Orr, H. M. Shingleton, Kenneth D Hatch, M. W. Trammel

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The effect of two β-adrenergic stimulating agents on bladder and urethral function was assessed in 16 patients 3 weeks after radical hysterectomy for carcinoma of the cervix. Urodynamic evaluation was performed before and after inhalation of metaproterenol by metered dose inhaler in 10 patients and injection of 0.25 mg of terbutaline sc in 6 patients. Although no change was observed following administration of metaproterenol, a significant decrease in maximum urethral pressure and urethral closure pressure, and a significant increase in volume of urine voided was found after administration of terbutaline. These results suggest that β-sympathomimetic agents may benefit those patients with bladder dysfunction following radical hysterectomy.

Original languageEnglish (US)
Pages (from-to)267-274
Number of pages8
JournalGynecologic Oncology
Issue number3
Publication statusPublished - 1986
Externally publishedYes


ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Oncology

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