The effect of breed, parity, and stage of lactation on conjugated linoleic acid (CLA) in milk fat from dairy cows

J. A. Kelsey, B. A. Corl, Robert J Collier, D. E. Bauman

Research output: Contribution to journalArticle

258 Citations (Scopus)

Abstract

Dairy products are the main source of conjugated linoleic acid (CLA), a functional food component with health benefits. The major source of cis-9, trans-11 CLA in milk fat is endogenous synthesis via Δ9- desaturase from trans-11 18:1, with the remainder from incomplete rumen biohydrogenation of linoleic acid. Diet has a major influence on milk fat CLA; however, effects of physiological factors have received little attention. Our objectives were to examine milk fat content of CLA and the CLA-desaturase index with regard to: 1) effect of breed, parity, and stage of lactation, and 2) variation among individuals and the relationship to milk and milk fat. Holstein (n = 113) and Brown Swiss (n = 106) cows were fed a single diet and milk sampled on the same day to avoid confounding effects of diet and season. Frequency distributions demonstrated that milk fat content of CLA and CLA-desaturase index varied over threefold among individuals, and this needs to be considered in the design of experiments. Holsteins had a higher milk fat content of CLA and CLA-desaturase index, but breed differences were minor. Parity and days in milk also had little or no relationship to the individual variation for these two CLA variables. Breed, parity, and days in milk accounted for <0.1, <0.3, and <2.0% of total variation in CLA concentration in milk fat, respectively. Milk fat content of CLA and CLA-desaturase index were essentially independent of milk yield, milk fat percent, and milk fat yield. We speculate that the basis for the genetic variation among individuals is related to rumen output of trans-11 18:1 and to a lesser extent cis-9, trans-11 CLA, and to the tissue amount and activity of Δ9-desaturase.

Original languageEnglish (US)
Pages (from-to)2588-2597
Number of pages10
JournalJournal of Dairy Science
Volume86
Issue number8
StatePublished - Aug 2003

Fingerprint

Conjugated Linoleic Acids
lactation stage
conjugated linoleic acid
Parity
Lactation
milk fat
Milk
dairy cows
Fats
breeds
lipid content
milk
Rumen
Diet
rumen
diet
biohydrogenation
Brown Swiss
breed differences
Functional Food

Keywords

  • Breed
  • Conjugated linoleic acid
  • Desaturase index
  • Milk fat

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)
  • Food Science

Cite this

The effect of breed, parity, and stage of lactation on conjugated linoleic acid (CLA) in milk fat from dairy cows. / Kelsey, J. A.; Corl, B. A.; Collier, Robert J; Bauman, D. E.

In: Journal of Dairy Science, Vol. 86, No. 8, 08.2003, p. 2588-2597.

Research output: Contribution to journalArticle

@article{a04b2c1789084b95b96894c514f4fd0d,
title = "The effect of breed, parity, and stage of lactation on conjugated linoleic acid (CLA) in milk fat from dairy cows",
abstract = "Dairy products are the main source of conjugated linoleic acid (CLA), a functional food component with health benefits. The major source of cis-9, trans-11 CLA in milk fat is endogenous synthesis via Δ9- desaturase from trans-11 18:1, with the remainder from incomplete rumen biohydrogenation of linoleic acid. Diet has a major influence on milk fat CLA; however, effects of physiological factors have received little attention. Our objectives were to examine milk fat content of CLA and the CLA-desaturase index with regard to: 1) effect of breed, parity, and stage of lactation, and 2) variation among individuals and the relationship to milk and milk fat. Holstein (n = 113) and Brown Swiss (n = 106) cows were fed a single diet and milk sampled on the same day to avoid confounding effects of diet and season. Frequency distributions demonstrated that milk fat content of CLA and CLA-desaturase index varied over threefold among individuals, and this needs to be considered in the design of experiments. Holsteins had a higher milk fat content of CLA and CLA-desaturase index, but breed differences were minor. Parity and days in milk also had little or no relationship to the individual variation for these two CLA variables. Breed, parity, and days in milk accounted for <0.1, <0.3, and <2.0{\%} of total variation in CLA concentration in milk fat, respectively. Milk fat content of CLA and CLA-desaturase index were essentially independent of milk yield, milk fat percent, and milk fat yield. We speculate that the basis for the genetic variation among individuals is related to rumen output of trans-11 18:1 and to a lesser extent cis-9, trans-11 CLA, and to the tissue amount and activity of Δ9-desaturase.",
keywords = "Breed, Conjugated linoleic acid, Desaturase index, Milk fat",
author = "Kelsey, {J. A.} and Corl, {B. A.} and Collier, {Robert J} and Bauman, {D. E.}",
year = "2003",
month = "8",
language = "English (US)",
volume = "86",
pages = "2588--2597",
journal = "Journal of Dairy Science",
issn = "0022-0302",
publisher = "Elsevier Limited",
number = "8",

}

TY - JOUR

T1 - The effect of breed, parity, and stage of lactation on conjugated linoleic acid (CLA) in milk fat from dairy cows

AU - Kelsey, J. A.

AU - Corl, B. A.

AU - Collier, Robert J

AU - Bauman, D. E.

PY - 2003/8

Y1 - 2003/8

N2 - Dairy products are the main source of conjugated linoleic acid (CLA), a functional food component with health benefits. The major source of cis-9, trans-11 CLA in milk fat is endogenous synthesis via Δ9- desaturase from trans-11 18:1, with the remainder from incomplete rumen biohydrogenation of linoleic acid. Diet has a major influence on milk fat CLA; however, effects of physiological factors have received little attention. Our objectives were to examine milk fat content of CLA and the CLA-desaturase index with regard to: 1) effect of breed, parity, and stage of lactation, and 2) variation among individuals and the relationship to milk and milk fat. Holstein (n = 113) and Brown Swiss (n = 106) cows were fed a single diet and milk sampled on the same day to avoid confounding effects of diet and season. Frequency distributions demonstrated that milk fat content of CLA and CLA-desaturase index varied over threefold among individuals, and this needs to be considered in the design of experiments. Holsteins had a higher milk fat content of CLA and CLA-desaturase index, but breed differences were minor. Parity and days in milk also had little or no relationship to the individual variation for these two CLA variables. Breed, parity, and days in milk accounted for <0.1, <0.3, and <2.0% of total variation in CLA concentration in milk fat, respectively. Milk fat content of CLA and CLA-desaturase index were essentially independent of milk yield, milk fat percent, and milk fat yield. We speculate that the basis for the genetic variation among individuals is related to rumen output of trans-11 18:1 and to a lesser extent cis-9, trans-11 CLA, and to the tissue amount and activity of Δ9-desaturase.

AB - Dairy products are the main source of conjugated linoleic acid (CLA), a functional food component with health benefits. The major source of cis-9, trans-11 CLA in milk fat is endogenous synthesis via Δ9- desaturase from trans-11 18:1, with the remainder from incomplete rumen biohydrogenation of linoleic acid. Diet has a major influence on milk fat CLA; however, effects of physiological factors have received little attention. Our objectives were to examine milk fat content of CLA and the CLA-desaturase index with regard to: 1) effect of breed, parity, and stage of lactation, and 2) variation among individuals and the relationship to milk and milk fat. Holstein (n = 113) and Brown Swiss (n = 106) cows were fed a single diet and milk sampled on the same day to avoid confounding effects of diet and season. Frequency distributions demonstrated that milk fat content of CLA and CLA-desaturase index varied over threefold among individuals, and this needs to be considered in the design of experiments. Holsteins had a higher milk fat content of CLA and CLA-desaturase index, but breed differences were minor. Parity and days in milk also had little or no relationship to the individual variation for these two CLA variables. Breed, parity, and days in milk accounted for <0.1, <0.3, and <2.0% of total variation in CLA concentration in milk fat, respectively. Milk fat content of CLA and CLA-desaturase index were essentially independent of milk yield, milk fat percent, and milk fat yield. We speculate that the basis for the genetic variation among individuals is related to rumen output of trans-11 18:1 and to a lesser extent cis-9, trans-11 CLA, and to the tissue amount and activity of Δ9-desaturase.

KW - Breed

KW - Conjugated linoleic acid

KW - Desaturase index

KW - Milk fat

UR - http://www.scopus.com/inward/record.url?scp=2142746929&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=2142746929&partnerID=8YFLogxK

M3 - Article

VL - 86

SP - 2588

EP - 2597

JO - Journal of Dairy Science

JF - Journal of Dairy Science

SN - 0022-0302

IS - 8

ER -